Bicyclohexyl-4,4’-dione was successfully synthesized by Salen Mn(III) catalyzed oxidation of bicyclohexyl-4,4'-diol using sodium hypochlorite as an oxidant and NBS as bromine source. The parameters including the Salen Mn(III) dosage, NBS dosage and sodium hypochlorite dosage were investigated. It was found that bicyclohexyl-4,4'-diol achieved a conversion of 96.1% and the selectivity of bicyclohexyl-4,4'-dione reached up to 93.0% under the optimum conditions: bicyclohexyl-4,4'-diol dosage 0.5 mmol, Salen-Mn(III) dosage 0.04 mmol, NBS dosage 0.26 mmol , sodium hypochlorite dosage 18 mmol, reaction temperature 25 ℃, and reaction time 0.5 h.