A micro-size eggshell Ni-based catalyst supported in fluid catalytic cracking catalyst residue (SFC3R) was synthesized by impregnation. The structure, morphology and reducibility of the catalyst were characterized by FIB-EDX、XRD、H2-TPR and TEM. The eggshell Ni/SFC3R catalyst was used for C5 petroleum resin hydrogenation，and the effects of temperature，pressure and reaction time were investigated. The properties and structure of hydrogenated C5 petroleum resin were analyzed by the method of Gardner color number， softening point， GPC， FT-IR and 1H-NMR. Results show that SFC3R contains zeolite structure and the Ni active component is mainly distributed in the outer layer of the SFC3R to form the eggshell distribution. The crystallite size of NiO of eggshell Ni/SFC3R catalyst is 21.5 nm, which exhibit good dispersion. The optimum conditions of C5 petroleum resin hydrogenation were found as temperature 280 ℃，H2 pressure 8.0 MPa and reaction time 4 h. The Gardner color of hydrogenated C5 petroleum resin is below 1# and the color is water white. The sulfur content and bromine number of hydrogenated C5 petroleum resin is <10mg/kg and 0.45 gBr/100g， respectively. And the unsaturated bond of C5 petroleum resin reaches saturation basically.