Abstract:A series of cinnamyl morpholine(2a~2i)were synthsized by the chlorination of substituted cinnamic acids(1a~1i)with thionyl chloride in DMAc at 0 ℃ for 20 min,followed by amidation in situ with morpholine at 25 ℃ for 7 h. The yield of 2a~2i were 81.6%~95.4%. The structures were characterized by 1H NMR、13C NMR、IR and MS. The proposed mechanism for the promotion of dimethylacetamid on the syntehsis was suggested.