SnO2 nanospheres were synthesized by hydrothermal method with Na2SnO3.4H2O as raw material and CO(NH2)2 as surfactant. The crystal structure, surface morphology and specific surface area were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Brunner-Emmet-Teller（BET）. Electrochemical performance was analyzed by electrochemical measurement. The results showed that the particle uniform dispersion and emidiameter size was about 400 nm and the Structure is typical of rutile phase. As an active material for lithium-ion batteries,the SnO2 nanospheres material’s first discharge capacity of 2206.6 mAh/g at a current density of 200 mA/g and at 0.01~3.0 V. The specific discharge capacity decreased to 440 mAh/g after 50 cycles. Data from this study indicated that SnO2 nanospheres material with high capacity and superior cycling stability.