For radioactive aerosols contaminated nuclear activities that might arise, a kind of water-soluble resin was synthesized based on acrylamide(AM) and acrylic acid(AA) via free radical copolymerization in aqueous solution for remove radioactive aerosols. The resin were characterized by FT-IR, 13CNMR and thermogravimetric(TG). The results shows that AM and AA reaction generated random copolymer P(AM-co-AA); The structure of different monomer ratio were also characterized by SEM , it demonstrates that the microstructure of copolymer with porous crosslinked networks in water phase related to the monomer ratio; Through surface tension analysis, it also shows that the monomer ratio affects the wettability of aerosols. The spray atomization experiment shows that the pressure can accelerate settlement of aerosol, has obvious effect of supressing.