otassium cobalt ferrocyanide was loaded on alkali-hydrolyzed waste leather to prepare a kind of adsorbent for Rb+ adsorption, whose structure and morphology were characterized with scan electron microscope (SEM), fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD). The effects of the mass ratio of Co(NO3)2•6H2O and K4Fe(CN)6•3H2O, pH, initial Rb+ mass concentration, adsorbent dosage, and contact time on adsorption capacity of adsorbent for Rb+ were investigated. The results showed that the adsorbent presented higher adsorption capacity for Rb+ when the mass ratio was 3:4. The adsorption efficiency was 93.55% at pH 7, adsorbent dosage of 0.09 g and initial Rb+ mass concentration of 20 mg/L, and adsorption achieved equilibrium at 6 h. The isothermal and kinetics of Rb+ adsorption on KCoFC-AWL were fitted well with Langmuir isotherm model and pseudo-second-order kinetics model. Up to 90% desorption efficiency of Rb+ was achieved with 1.5 mol/L KCl. The adsorption efficiency reached up to 51.19% when the adsorbent was utilised to adsorb Rb+ from saline lake at pH 7, indicating its potential application advantages as an efficient adsorbent.