Using Butyl methacrylate(BMA), 2-ethylhexyl methacrylate(2-EHM) and styrene(St) as raw material, polyvinyl alcohol(PVA) as dispersant agent, benzoyl peroxide(BPO) as initiator, divinylbenzene(DVB) as crosslinking agent, modified attapulgite as inorganic additive to prepare high oil-absorption resin with microwave irradiation. The major influences, including mass fraction of initiator，styrene, OATP and reaction temperature were studied. Meanwhile, the structure, thermal performance and surface topography of oil-absorption resins were analyzed by FTIR, TGA and SEM, respectively. The result shows: when w(St)=52.54%、m(2-EHM) : m(BMA)=1:1.5、w(BPO)=1.95％、w(DVB)=0.6％、w(PVA)=3％、w(OATP)=2.0％，at 82℃,reaction time is 70min, microwave power is 700W, it has the maximum oil absorbency to carbon tetrachloride, dichloromethane, toluene and xylene. That is 37.24, 30.50, 16.94 and 16.81g/g, respectively, the thermal decomposition temperature of the resin was improved 32℃ after adding OATP into the resin.