Sodium hypochlorite (NaClO) was synergistically activated with Peroxymonosulfate (PMS) and ozone (O3) to treat simulated printing and dyeing wastewater. The indicators are the degradation rates of dyes such as Rhodamine B (RhB), Reactive Brilliant Blue (Knr), Reactive Red (X-3B), and Methyl Orange (MO). UV-visible absorption spectroscopy analysis method is used to explore the influence of factors such as the ratio of material mass, pH, Cl-, NO3-, SO42-, and HCO3- in wastewater. The results show that the ratio of the optimum mass of NaClO-PMS and NaClO-O3 systems are n(NaClO): n(PMS)=1:1 and n(NaClO):n(O3)=2:3, which have good degradation of RhB at the pH of 3-11 and 3-9, respectively. The NaClO-PMS system has better degradation of RhB under acidic conditions, the degradation rate reaches 96.18% at pH=3. The NaClO-O3 system has a good degradation effect on RhB under the neutral pH con-dition, and the degradation rate reaches 97.91% at pH=7. The concentration of anions have a little influ-ence on the treatment effect of printing and dyeing wastewater by NaClO-PMS or NaClO-O3 system.