Loofah graft copolymers (loofah-g-PDMAEMA) was synthesized via electron transfer for atom transfer radical polynerization(ARGET ATRP), using loofah with bromide side-group(loofah-Br) as the macroinitiator and N,N,N′,N′,N″-pentamethyldiethylenetriamine (PMDETA)/copper(Ⅱ) bromide(CuBr2) as catalytic system, vitamin C as reducing agent. Chemical structure, crystalline structure and thermal stability of modified loofah were characterized by fourier transform infrared spectroscopy(FT-IR), thermogravimetric analysis(TGA). The lead adsorption and repeated adsorption performance of the loofah-g-PDMAEMA were studied. The results indicated that loofah-g-PDMAEMA possesses good adsorption capacity of Pb2+. loofah-g-PDMAEMA achieved the maximum adsorption capacity of 107.8mg/g under the best adsorption conditions when the temperature was 30°C, the pH was 5.5, and adsorption time was 5h. The adsorption process was conformed well to the pseudo-second-order kinetic model. Besides, after 5 reuses, the adsorption capacity can reach 84.73% of the first adsorption.