A new coagulant, poly-Ti-Fe (M-PTF), was prepared using a solid “waste acid filter cake (WAFC)” derived from production process of titanium dioxide. The microscopic characteristics of M-PTF were characterized with SEM, XRD and FTIR, respectively. And coagulation performance and sludge properties of M-PTF in treating a domestic wastewater was studied using Jar tests and Fluorescence Microscope (FM), compared with that of Poly Aluminum Chloride (PAC). The results showed that M-PTF surface morphology was composed of irregular and crystalline-like structures, and appeared to be rough and polymorphous networks having larger surface area. M-PTF gave higher 29% organic matter (Chemical Oxygen Demmand, CODCr) removal than PAC at dosage 2 mmol/L, and had far greater sludge settling rate at starting point (44 mL/min) than PAC (4 mL/min). M-PTF sludge was a sort of fluffy and close-ly-connected catkins-like/cotton-like images with well-defined boundary and lower water content, while PAC almost appeared to be a sort of transparent loose flocs without well-defined boundary. M-PTF sludge volume was much smaller than PAC and the water content of M-PTF sludge was lower 1.11%~2.41% than that of PAC, corresponding to its sludge reduction of 71.28%~84.38% based on the sludge volume of PAC, largely beneficial to subsequent concentrating and dewatering.