A compound N-[2-(Dimethylamino)ethyl]-2,2,2-trifluoroacetamide (NDAET) was obtained by acylation using ethyl trifluoroacetate and N,N-dimethylethylenediamine as raw materials.Then quaternization of NDAET with bromododecane to obtain a novel fluorinated quaternary ammonium salt surfactant (NDAET-12).The structure were characterized by FTIR，1 HNMR and 13 CNMR．The surface performance results showed that NDAET-12 had a high surface activity，the critical micelle concentration of the aqueous solution was 4.62?10-2mmol/L and the corresponding CMC surface tension was 24.78 mN/m.