N-Isobornyl Acrylamide (NIBAM) was synthesized from acrylonitrile and natural renewable resource camphene under solvent-free conditions. Effects of the types and the dosages of catalysts, molar ratio of camphene to acrylonitrile and water, reaction temperature and reaction time on the reaction selectivity and the yield of NIBAM were investigated, and the optimum reaction conditions were determined by or-thogonal tests as follows: the molar ratio of camphene to acrylonitrile and water was 1:3:1; FeCl3 was adopted as the catalyst, and the amount of FeCl3 was 10%; reaction temperature 120 ℃, reaction time 12 h. The reaction electivity and the average yield of NIBAM under the aforesaid conditions were 90.3% and 97.6%, respectively. The structure of NIBAM was determined by HRMS, FT-IR and NMR.