Nano-scale TS-1 molecular sieves were synthesized using low-cost reagents (silicasol and tetraprop-ylammonium bromide) by steam-assisted method with assist of seeds. The molecular sieve was post-modified using ethylamine and tetrapropylammonium bromide mixed solution by secondary hydro-thermal crystallization. Then, the TS-1 zeolite with high catalytic activity containing hexacoordinate tita-nium was produced. Then it was characterized by X-ray diffraction, UV diffuse reflectance visible spec-trum, ultraviolet Raman spectroscopy, Fourier transform infrared spectroscopy, solid state nuclear mag-netic resonance, N2 physical adsorption-desorption. Finally, the epoxidation of propylene was used as a probe reaction to evaluate the catalytic performance of the samples. The results showed that the nano-scale TS-1 synthesized by post-modification with hexacoordinate titanium species possessed im-proved pore structure and obviously increased specific surface area. The activity of catalyzing the epoxi-dation of propylene was obviously improved. The conversion rate of hydrogen peroxide was significantly increased from 47.59% to 85.79%.