Abstract:With hexadecyl trimethyl ammonium bromide (CTAB) as template agent, triethanolamine (TEA) as a catalyst, ethyl orthosilicate (TEOS) as silica source, calcium nitrate tetrahydrate (CaNT) as the calcium source, triethyl phosphate (TEP) as a source of phosphorus, dendritic mesoporous bioglass RMBG1, RMBG2, RMBG3 were prepared by using the sol-gel method at different temperatures (40 ℃, 60 ℃, 80 ℃). Then, the template agent was removed by calcining at high temperature. The morphology, structure, particle size and stability of dendritic biological glass at different reaction temperatures were characterized by field emission scanning electron microscope (FESEM), transmission electron microscopy (TEM), automatic fast specific surface area and voidage analyzer (BET), nano particle analyzer. The results show that the prepared dendritic mesoporous biological glass RMBG2 at 60 ℃ possess uniform particle size, good dispersion and large specific surface area. It’s particularly that it displays unique structural advantage of three-dimensional open dendritic channels. The qualitative analysis of X-ray electron spectroscopy shows that RMBG2 contains Si, Ca and P elements. The inductively coupled plasma (ICP) shows that the approximate ratio of three elements of RMBG2 (Si: Ca: P) is 84:14:2. The specific surface area of RMBG2 is as high as 821.161m2g-1, The pore size is 3.184 m3.g-1 can be used as an efficient drug carrier.