Mustard gas is known as the "king of chemical warfare agents" and is a typical class of erosive chemical warfare agents. Catalytic degradation has the characteristics of high efficiency and good safety. It can not only degrade mustard gas but also prevent to degrade into other highly toxic products, such as toxic sulfone products. The materials used for catalytic degradation mainly include hypochlorite, hydrogen peroxide, enzymes, and metal-based catalysts. Among them, the metal-based catalyst has mildness, high efficiency and high selectivity, and the mustard gas is degraded into non-toxic products mainly through oxidation reaction, hydrolysis reaction and dehalogenation elimination reaction. This paper summarizes of the metal-based catalysts such as metal oxides, polyoxometalates (POMs), metal organic framework materials (MOFs) for the degradation of mustard gas and the principle of degrading mustard gas. The production method of metal-based catalyst material for degrading mustard gas was summarized. Finally, The research directions in metal oxides, POMs and MOFs are prospected so as to provide new ideas for subsequent research.