The isophorone diisocyanate trimer (FIPDIT) grafted with organic fluorine was synthesized by melt polycondensation of 2,2,3,3,3,3-tetrafluoro-1-propanol (PFIP) and isophorone diisocyanate trimer (IPDIT). The graft of silicone-containing waterborne polyurethane (FSWPU) with organic fluorine was prepared from isophorone diisocyanate (IPDI), polyether diol (N210), hydroxyl polydimethylsiloxane (PDMS), 1,4-butanediol (BDO), 2,2-dihydroxymethyl propionic acid (DMPA) and different dosage of F-IPDIT. the FSWPU structure and properties were characterized by FTIR、TGA、 water contact angle, stretching and solvent resistance. The results show that the emulsion is stable, Under n (N210): n (PDMS)=8∶1, And when the FIPDIT is 5%, Average particle size 168 nm, Water absorption is 8.1%, Contact angle 113.5°, 23.1 Mpa, tensile strength, The elongation at break is 328%, the temperature of 10%,30% and 50% of the thermogravimetric weight loss was 302、329、350℃, respectivel. The water resistance, solvent resistance, et al, are obviously improved.