In order to improve the hydrophobicity property of titanium dioxide and solve the problems in its low dispersibility and compatibility in organic solvents, the surface of titanium dioxide powder was modified by using fluorine-hydrovinyl polysiloxane (F-PMHS). The structures and superhydrophobic properties of the modified TiO2 were studied by FT-IR, TGA, SEM, contact angle tests and sedimentation experiments. The formation mechanism of the superhydrophobic surface was also analyzed in detail. The results showed that when the mass fraction of F-PMHS relative to TiO2 is only 8%, the static contact angle between the modified TiO2 coating and water can reach 152.4 ° with good superhydrophobic properties, and the dispersion and compatibility of TiO2 in organic solvents are significantly improved.