In this study, using micron diatomite and nanometer alumina particles as raw materials, the surface with a certain rough structure was constructed. Using cetyltrimethoxysilane (HDTMOS) as low surface energy modifier and epoxy resin as adhesive, the diatomite /Al2O3 composite superhydrophobic coating was prepared. Firstly, diatomite and alumina particles were surface modified by HDTMOS hydrolyzate, and then epoxy resin solution was added to obtain suspension. The suspension was sprayed on the surface of the substrate by spraying method, and the superhydrophobic coating was obtained after heating and curing. The optimum preparation process (V(HTDMOS)∶V(ethanol)=0.04∶1; m (diatomite)∶ m (Al2O3) =1.5∶0.8; m (E51)∶ m(acetone) =1∶5), the water static contact angle of the surface is as high as 163.4°, and the surface is characterized by uniform microstructure by scanning electron microscopy. The coating is suitable for filter paper, wood block, stainless steel plate and other substrates, which can show excellent superhydrophobic properties. Meanwhile, the surface water static contact angle of the coating is still as high as 146.3° after 100 cycles of wear experiments.