In order to study the influence of the carrier on the physical and chemical properties of pesticide solid nanoformulations and its selection principles, the emamectin benzoate solid nanodispersions with seven different carries were prepared by self-emulsifying and solidification technology. The powder size, solubility, specific surface area and morphology of the carriers were compared. Furthermore, the effects of the carriers on the particle size, dispersibility, interfacial charge, pH, crystallinity and foliar wettability of the solid nanodispersions were revealed.The physicochemical properties and structures of the carriers have a significant impact on the particle size, dispersibility, interfacial property and crystallinity of the solid nanodispersion.Sodium benzoate and sodium butyrate were excellent carriers for emamectin benzoate solid nanodispersions. The particle sizes of the solid nanodispersions with sodium benzoate as carriers was 22 nm and the PDI was 0.358.