A series of tristyryl phenol polyoxyethylene ether sulfates salt (TSPOES) with different ethylene oxide (EO) numbers were synthesized with tristyryl phenol polyoxyethylene ethers (TSPOE), sulfamic acid and urea as original materials. Liquid disperse dyes were prepared using TSPOES as dispersant, and the storage stability of liquid disperse dyes was explored through particle size analysis, then the dyeing properties of liquid disperse dyes with good storage stability were explored. The results showed that the content of anionic active substances（ TSPOES )was above 85% when the molar ratio of TSPOE to sulfamic acid was 1:1.6. With increasing of the EO number of dispersant TSPOES, the particle size and PDI of the prepared liquid disperse dyes decreased first and then increase. When the EO number of dispersant TSPOES was 20, the particle size of the prepared liquid disperse dyes was 165.9 nm, the according PDI was 0.195. At the same time, its storage stability