Abstract: In this paper, CdS/RGO/MoS2 composites were prepared by simple hydrothermal method. They were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), UV-visible diffuse reflectance spectroscopy (UV-VIS DRS), electrochemical impedance (EIS) and transient photocurrent response. The results showed that CdS/0.75 wt % RGO/ 1.0 wt % MoS2 composite had significant photocatalytic degradation activity and stability for methyl orange (MO) under visible light irradiation. The photodegradation rate (0.05777 min-1) was 2.5 times than that of CdS (0.023 min-1), 19.3 times than that of MoS2 (0.003 min-1), 2 times than that of CdS/0.75 wt% RGO (0.02821 min-1) and 2.16 times than that of CdS/1.0 wt% MoS2 (0.02677 min-1)，respectively. After 5 cycles, the degradation effect did not change significantly, which proved that the catalytic system had good stability. The increase in photocatalyst activity was mainly due to the formation of composite materials, enhancing the separation and migration of carriers. These materials had excellent photocatalytic performance and good stability for the photodegradation of MO under visible light irradiation, thus had a wide range of application prospects and theoretical significance.