Using glycidyl oleate and glycerol as raw materials, under the action of solid acid catalyst（sulfuric acid supported on activated carbon）, dipolyglycerol oleate is prepared by ring-opening reaction. The structure of the product was analyzed and characterized by FTIR and 1HNMR, and it was used as a softening and moisturizing agent to be coated on facial tissue to study the paper's properties such as softness, moisture retention, and tensile strength. The results show that dipolyglycerol oleate has excellent softening and moisturizing properties. When the amount of dipolyglycerol oleate is 0.25% of the mass of glycerin aqueous solution, the softness (49 mN) of facial tissue is better than that of silicone softeners on the market. The softness of the modified facial tissue (68 mN) is due to the fact that the macromolecular softener can repair the defects on the fiber surface, thereby improving the flatness of the fiber surface. And when the temperature is 30 ℃ and the humidity is 60%, the water retention rate (98.2%) of the facial tissue coated with dipolyglycerol oleate softener is also slightly higher than that of the facial tissue coated with silicone softener (96.5%).