N-coconut-1,3-propylbisguanidine acetate (CPGA) was synthesized from N-coconut-1,3-propyldiamine (CPDA), cyanamide and acetic acid. The product was characterized by FT-IR and MALDI-TOF MS. The stabilities, wettabilities, emulsification abilities, foam properties, detergency performances and bacteriostatic activities of CPGA compounded with three anionic surfactants (fatty alcohol carboxylate AEC9-Na, sodium lauryl polyoxyethylene (3) ether sulfate AES, sodium dodecyl benzene sulfonate LAS) and two non-ionic surfactants (fatty alcohol polyoxyethylene ether AEO9, C12~14 alkyl polyglucoside APG1214) were studied. The results showed that the AEC9-Na/CPGA compounded system was transparent, which exhibited the excellent wettability, emulsification ability, foam property, detergency performance and bacteriostatic activity，especially the bacteriostatic rate of Staphylococcus aureus and Escherichia coli reached 75% and 91% at the concentration of 0.02 g/L, superior to the other four compounded systems. Therefore, the AEC9-Na/CPGA compounded system had a good development prospect in antibacterial detergents.