The influence of ZrO2/Al2O3 ratio on the catalytic performance of hydrogenolysis of glycerol over Pt supported on four-component oxides, namely WO3-TiO2-ZrO2-Al2O3 was systematically studied. The catalyst structure was characterized by several techniques such as BET, XRD, CO adsorption and pyridine adsorption FT-IR, and H2-TPR. The results suggested that introducing Al2O3 into the four-component oxides favors the dispersion of tetragonal phase ZrO2, on which highly dispersed Pt nanoparticles and monoclinic phase WO3 with strong metal-support interaction were formed. Thus formed structure benefits to the formation of Bronsted acid sites which improve the selectivity toward 1,3-propaneodiol. When ZrO2/Al2O3 was 9:1 in weight, the Pt/WO3-TiO2/ZrO2-Al2O3 catalyst showed 39% glycerol conversion and 1,3-PDO selectivity of 49% within 100 hours in a fixed-bed reactor.