Parafuchsin was synthesized by a two-step catalytic method. Firstly, para-nitrotoluene was used as the starting material, and sodium polysulfide was combined with ethanol as the organic solvent and N, N-dimethylacetamide(DMA) as the amine catalyst. The results showed that n (DMA) : n (p-nitrotoluene) =3:13 reaction effect was the best. Then, under the catalyst of alcohol based catalyst polyethylene glycol 400 (PEG-400), it reacted with aniline and hydrochloric acid to produce para-magenta crude product. The effects of material ratio, reaction temperature and reaction time on the yield of para-magenta crude product were investigated. The results showed that n (PEG-400) : n (p-nitrotoluene) =2: 300, n (p-nitrotoluene) : n (aniline) : n (hydrochloric acid) = 1: 5.9:2.8, reaction at 110 ℃ for 4 h, the yield of para-magenta crude was 85.6% .In the process of parafuchsin purification, the effects of reaction temperature and time on the mass fraction of parafuchsin were investigated, The results showed that the mass fraction of parafuchsin reached 99.3% after reaction at 130℃ for 3h. The wastewater from parafuchsin production is mainly aniline. After rectification, 89.3% of aniline can be recovered. The process has the characteristics of green, high efficiency and environmental protection, and is conducive to industrial popularization.