In order to obtain a new pesticide formulation with high drug loading and good dispersion property, based on drug delivery theory, a pesticide delivery system (PDS) with a special micro/nano composite structure was constructed by electrospinning technology with avermectin (AVM) as the pesticide model, ethyl cellulose (EC) as the main pesticide carrier, and carbomer (CB) as the modified material. Through the exploration of compound proportion, dissolution parameters and spinning conditions, the results show that: The mixed solvent of N, N-dimethylacetamide and ethanol was used to dissolve the carrier material EC and CB. When the volume complex ratio of EC and CB spinning solution was 1:1, the loading rate of AVM in PDS was up to 35.7%, the encapsulation rate of AVM in PDS was close to 100%, and the photolysis resistance was greatly improved. Besides, this PDS has excellent property of water dispersion, long duration of efficacy.