Purely organic long-persistent luminescent materials are widely used in the fields of anti-counterfeiting, information security, biological imaging, and other applications due to their benefits of ease of synthesis, low cost, flexibility, and environmental friendliness. Among them, organic long-persistent luminescence materials based on doping systems have become a current focus of research for long-persistent luminescence materials because they enable the adjustment of luminescent time and color by controlling the coordination relationship between host and guest. This article reviews the developments in the disciplines of micromolecular, macromolecular, and polymer matrix research, as well as the uses of related materials in fields such as information security and counterfeit prevention, biological imaging, flexible fiber film, and others. Finally, some problems existing in the research area are pointed out, and their development prospects are prospected.