In recent years, mechanical grinding chemistry has attracted much attention by synthetic chemists for its solvent-free conditions. Here we reported a method for the selective oxidation of sulfides to prepare sulfoxides or sulfones by ball milling at room temperature without solvent. A series of sulfones or sulfoxides were selectively prepared with 90%~99% yields from sulfides by adjusting the size and number of grinding balls (proportion of large, medium and small is 20∶40∶100), ball milling time (5~50 min), rotational velocity (400 rpm) and equivalents of Oxone (1~4 mmol) as an oxidant under grinding conditions. All the structures were confirmed by 1HNMR and 13CNMR. This method has benefits of good selectivity, high yield, and wide substrate tolerance, which expands the application scope of mechanochemistry.