Currently, due to the high demand for livestock and poultry farming and fisheries, tetracycline antibiotics are used in large quantities, which poses a threat to the environment and public health. This review introduces the main components of tetracycline antibiotics and their harm in the environment, and summarizes the methods of degradation and treatment of tetracycline antibiotics. This review mainly summarizes the advanced oxidation technology, the performance control strategy, and the new advanced oxidation strategy. Due to the difficult characteristics of tetracycline antibiotics, a single advanced oxidation technology cannot completely degrade them, and it is usually necessary to regulate and combine the performance of advanced oxidation technology to completely degrade them. At present, there are many new advanced oxidative degradation strategies with outstanding performance in degrading tetracycline antibiotics, including biological coupling chemistry, photocatalysis, photo-Fenton method, electric-Fenton method, ozone-electrochemical coupling method and low temperature plasma technology. These new approaches aim to achieve more comprehensive and effective degradation of tetracycline antibiotics.