The brittleness of epoxy resin limits its applications and it must be toughened to meet the requirements of industry. Herein, bio-based eugenol-silicone epoxy resin was developed via etherification and heterogeneous hydrosilylation reactions using eugenol, epichlorohydrin, as well as heptamethyltrisiloxane as feedstocks and it was then used to toughen bisphenol A epoxy resin (E-51). Toensurethequalityandauthenticityoftheproduct,Fouriertransforminfraredspectroscopy(FT-IR),nuclearmagneticresonance(1HNMR),differentialscanningcalorimetry(DSC),andauniversaltestingmachinewereemployedforcomprehensivecharacterizationandperformancetesting.TheFT-IRand1HNMRanalysisconfirmedthesuccessfulsynthesisofthetargetproduct,ES-EP.Distinctively,the? heterogeneouscatalyzedhydrosilylationreactionachievedaconversionrateof91%,andthecatalyst canberecycled.Furthermore,theepoxyvalueoftheproductwasdeterminedtobe0.251mol/100g. Compared to the reference sample, when 10wt% ESEP was incorporated into the epoxy resin system, the tensile strength, flexural strength, and impact strength of cured product (10%ES-EP/E-51) were remarkably increased by 21.49%, 18.01%, and 31.59%, respectively. Additionally, the glass transition temperature and thermostable temperature were both higher than the traditional epoxy resin (approximately 10℃). All of the results indicated that eugenol-silicone epoxy resin could efficiently