Abstract:In this paper, the characteristics of waterborne polyurethane (WPU) and its research progress of new technologies on modifying WPU resin were introduced. The main problems in production and application of synthetic leather used WPU resin were discussed. However, since the hydrophilic group is brought into , WPU is weak in water resistance , solvent resistance, water vapor permeability, compatibility and rate of drying, hence , researchers are modifying WPU, such as the acrylate modification, organic silicon modification, organic fluorine modification, vegetable oil modification, epoxy resin modification, nanometer materials modification, and hyperbranched polymer modification etc. The use of radiation technology, including radiation polymerization, crosslinking and curing, in copolymer latex is reviewed in the paper. The likely future trends of the modification design of synthetic leather used WPU resin were described.

Abstract:The static adsorption properties of alkaloids in nine kinds of macroporous resins were evaluated. The H103 macroporous resin which displayed the best adsorption capacity among the tested resins was selected out; the adsorption isotherm curve and adsorption kinetic behaviour of alkaloids with H103 macroporous resin were systematically studied, then the dynamic adsorption and desorption capability of alkaloids on H103 resin-packed column was investigated to establish optimal parameters for separation of matrine and oxymatrine. The different eluent was detected by thin layer chromatography (TLC), the sample of matrine or oxymatrine was detected by high performance liquid chromatography (HPLC). Results showed that the adsorption isotherm could be described by Freundlich isotherm equation; According to dynamics adsorption curve, the balance time was 100 minutes, Adsorption kinetic law could be expressed by Pseudo-second-order; the optimized dynamic process for gradient elution was 30% C2H5OH-25% NH4OH (115:1, v/v) and 80% C2H5OH, the oxymatrine was eluted firstly with recovery yield 85.3%, then matrine was eluted with recovery yield 90.1%, these two alkaloids could be separated effectively.

Abstract:In this paper, the key intermediate of 2-methoxylcarbonyl-5-methylsulfonylaminomethylbenzene sulfonamide (6) was prepared starting from p-tolunitrile via chlorosulfonation-aminiation, oxidation, reduction, methlsulfonylation and alcoholysis. Subsequently, the aimed product of mesosulfuron-methyl (7) was achieved from 6 and 4,6-dimethoxy-2-(phenoxycarbonyl)aminopyrimidine, the total yield of the six-steps was 33.3%. The structures of target product and intermediates were determined by IR, 1H NMR and MS. Compared with the synthesis process in references, this synthetic route is cost-effective, simple operation, high yield and valuable for the industrial application.

Abstract:1,4-Naphthoquinone was prepared by oxidation of 1-naphthylamine with manganese ore powder as oxidant in sulfuric acid, which first reacted with 1-naphthylamine to form the related ammonium sulfate. The effects of reaction temperature, oxidation time, reactant molar ratio, types of acids, concentration of sulfuric acid on the product yield were investigated in detail. The optimal reaction conditions were as follow: 1-naphthylamine 1.8 g, n(1-naphthylamine) : n(MnO2) = 1:7, mass fraction 40% sulfuric acid 61 g, reaction temperature 80°C, reaction time 3 h. The yield of 1,4-naphthoquinone was above 59.8% in this condition. This new developed process has the advantages of convenient operation, easy separation of the product and short productive period.

Abstract:The 2-picolinate complexes M(C5H4NCOO)2?xH2O of cobalt(II) and nickel(II) were synthesized with cobalt acetate, nickel chloride and 2-pyridinecarboxylic acid as the reactants by solid-state reaction at room temperature. The compositions and structures of the complexes were characterized by EDTA titration, elemental analysis, FT-IR spectrum, X-ray powder diffraction, thermogravimetric and differential thermal analysis. The results of characterization showed that the cobalt(II) and nickel(II) were coordinated by the heterocyclic nitrogen atoms and carboxyl oxygen atoms of the ligands, and oxygen atoms from the water molecules, respectively. Thermal decomposition processes of the complexes included dehydration, oxidation and pyrolysis of the ligand, and finally as metallic oxide.

Abstract:The influences of titanium precursor, base type and temperature on morphology of the titanate nanofiber（TiNF） synthesized by hydrothermal method were studied. It is found that the precursor of amorphous titania gel and base of KOH are both leading to the generation of nonporous TNFs and an evenly distributed and elongated TNFs were synthesized at 90℃ with the length to diameter ratio of 1000 and specific area of 311m2/g. Taking thus made TiNFs as the support, a solid base catalyst was prepared by impregnation of the alkaline halide which has demonstrated excellent basic activity in synthesis of propylene glycol monomethyl ether at lower temperature and shorter time by methanol addition reaction of epoxy propane. Temperature programmed desorption of CO2 test has found the amount of the basic sites on catalyst surface doubled after impregnation of alkaline halide on the blank TiNF support and also appeared the new basic sites of medium and strong strength.

Abstract:Thermo-responsive hydrogels were synthesized by N-ispropylacrylamide(NIPAM) and acrylamide(AM) with N,N'-methylenebiscrylamide(BIS) as crosslinker, ammonium potassium and sodium bisulfite as initiators. The effects of the properties were studied by the change of feed composition. The results show that with the increase of hydrophilic monomer AM, the swelling ratio, water retention and hardness of P(NIPAM-co-AM) are enhanced. The hardness increases from 84.929g in absence of AM to 1255.222g when AM is 100%. According to DSC, when the dosage of AM increases from 2% to 10%, the LCST of P(NIPAM-co-AM) gel increases from 38.61℃ to 57.95℃. With the decrease of AM content, LCST of P(NIPAM-co-AM) gel declines, the responsibility is improved.

Abstract:A new PCBM-like fullerence derivative [6,6]-phenyl-C61-butyric acid isopropyl ester (PCBIP) was designed and synthesized. The structure of PCBIP was characterized by UV-Vis, FT-IR, 1H NMR, 13C NMR, MS and elemental analysis techniques. The LUMO and HOMO level of PCBIP are higher 0.029 eV than PCBM by simulate calculation. The thermal stability of PCBIP was studied by differential thermal analysis (DTA) and thermogravimetric analysis (TG), and the results proved that PCBIP has good thermal stability. We expected that the open-circuit voltage (Voc) and energy conversion efficiency (PCE) of polymer solar cells can be improved when it as the acceptor material.

Abstract:English abstract The purpose of this experiment is the design and synthesis of a pH-responsive, amphiphilic block copolymers of the low toxicity of the polymer micelles for drug delivery.Amphiphilic biodegradable diblock copolymer of poly(ε-caprolactone) (PCL)-monomethoxy poly(ethylene glycol) (mPEG) was synthesized by ring-opening polymerization of ε-caprolactone with a mPEG as initiator.The doxorubicin was then attached to the PCL terminus via acid-cleavable cis-aconityl. The diblock copolymers were characterized by 1H NMR, FTIR et al. Doxorubicin-conjugated mPEG-PCL diblock copolymers self-assembled to form micelles in aqueous solution,the particle sizes determined by DLS were about 45.4 nm, TEM images showed that these micelles were regularly spherical in shape. The release rate of DOX from micelles at pH 4.0 was observed much faster than that at pH 7.4.The mPEG-PCL copolymer was nontoxic in cell culture, whereas DOX-loaded micelles exhibited time-delayed cytotoxicity in human MCF-7 breast cancer cells. The intracellular localization of free DOX, mPEG-PCL-DOX micelles in MCF-7 were observed by confocal laser scanning microscopy, showed that carrier can take DOX to be entered the cells.

Abstract:Both ends of hydrogen of polydimethylsiloxane (HPDMS) was synthesized with octamethylcyclotetra- siloxane(D4) and 1,1,3,3-Tetramethyldisiloxane(HMM) as raw material. Allyl polyoxyethylene chlorhydrin ether (APECAE) was synthesized with allyl polyoxyethylene ether(APEG) and epichlorohydrin as raw material.Quaternary ammonium salt allyl polyoxyethylene chlorhydrin ether(QASAAE) was prepared by the cationization from octadecyl dimethyl tertiary amine and APECAE. Quaternary ammonium salt organic silicon of Gemini surfactant (Gemini-QASPSS) was prepared by the hydrosilylation from HPDMS and QASAAE. The chemical structure of Gemini-QASPSS was characterized by IR and 1HNMR.The interfacial properties of Gemini-QASPSS were studied by the measurement of equilibrium surface tension in its aqueous solution. The results show that in the critical micelle concentration of 5.3?0-5mol稬-1, the surface tension of Gemini-QASPSS aqueous solution reduced to approximately 24.5 mN穖-1. The saturated adsorption, single Gemini-QASPSS molecular average areas on the saturated absorption layer and the micellization standard free energies are 1.6?0-6mol穖-2, 1.08 nm2 and -28.6 kJ穖ol-1, respectively.

Abstract:Since there was lack of Low-foaming penetrating agents in the market, octyl/decyl polyethylene oxide (OEO) was modified in this paper by silicone-capping to improve its low-foaming property and maintain its excellent penetrating property in the meantime. Three novel penetrating agents were synthesized from OEO and three kinds of methyl chlorosilane reagents and confirmed by FTIR and 1H-NMR. Both foaming volumes and penetrating times against concentrations of penetrating agents were investigated in the concentration ranges used by commercial penetrating agents (0.1 wt.%~0.25 wt.%). Hydrolytic stabilities of these penetrating agents were expressed by means of the variation of foaming ratio against time. The experimental results showed that two of three novel penetrating agents maintained the excellent penetrating property and hydrolytic stability, and all of them displayed much better low-foaming properties than OEO.

Abstract:Polyethoxy esterquat (3EQDMS－nEO) was prepared via ethoxylation of an tri-ester formed by reaction of stearic acid and triethanolamine and quaternization of the ethoxylated tri-ester．Structure of the product was characterized by FTIR and 1HNMR．The softening，rewettability，detergency and impact on fabric whiteness of the product were studied and compared with that of EQDMS．Results showed that the 3EQDMS-6EO is an excellent softener. The softening property of the product is close to that of EQDMS．Its rewettability is better than that of EQDMS，and impact of the product on the fabric whiteness is not big．3EQDMS-6EO has the certain detergency while EQDMS dose not.

Abstract:Abstract：In order to evaluate the safety and physiological function of nicotine metabolic, using the method of biological synthesis preparation of L-6-hydroxy nicotine. we prepared the nicotine metabolic intermediate which is called L-6-hydroxynicotine by Arthrobacter Z3 using nicotine as substrate. We found that by using the analytical HPLC, when the fermentation reacted for 24h, the amount of the target product accumulation reaches the maximum. We take ethyl acetate: methanol: a mixed solution of aqueous ammonia (6:1:0.01) as eluent, the fermented crude product was separated and purity of the target product is 99.00% detected by HPLC. After identified by IR, 1HNMR, 13CNMR and MS, nicotine metabolic intermediate L-6-hydroxynicotine was confirmed.

Abstract:Extraction of arecoline from Areca inflorescence at different blossoming stage by heat reflux. With yield of arecoline as index, the samples were determined by HPLC. The result showed that the yield of arecoline was 4.96±0.067 mg/g，4.26±0.14 mg/g and 2.02±0.16 mg/g in beginning flower, open flower and ending flower respectively. The result indicated that the arecoline content was coming down with the Areca inflorescence was becoming mature at different flavoring period. It will provide the reference for the harvesting and processing of Areca inflorescence. Key words: Areca inflorescence; Areca inflorescence tea; Areca inflorescence wine; arecoline; HPLC

Abstract:For studying about the medicinal active ingredients of Gonocaryum lobbianum(Miers) Kurz and promoting the development and utilizing the resource well, antioxidant and antibacterial activities of extracts from the G. lobbianum(Miers) Kurz root, stem and leaves with five different kinds of solvents are researched in this assay. Antioxidant activity is determined by the method of DPPH?. Antibacterial activity is performed by filter paper tablet diffusion method against five kinds of microorganism strains. The results show IC50 value of scavenging DPPH? of ethyl acetate (EtOAc) extract from leaves（L-EtOAc） is 154.1μg/mL , which is minimum, so L-EtOAc has the strongest antioxidant activity . All fifteen extracts from G. lobbianum(Miers) Kurz root, stem and leaves show different antibacterial activities on the tested bacteria. However, L-EtOAc has the strongest inhibitory activity on the tested bacteria, especially on the Staphylococcus aureus, Escherichia Coli, Pseudomonas aeruginosa, which is similar with the positive drugs ceftazidime. In a word, the antioxidant and antibacterial activities of EtOAC extracts from G. lobbianum(Miers) Kurz leaves are strongest.

Abstract:Coconut shell activated carbon (AC) was used as carrier to covalently immobilize Pd2 complex. The content of hydroxyl groups on the carbon surface was increased to 0.383 mmol/g after 20% HNO3 oxidation. Nitrogen-containing bidentate ligand was synthesized by grafting the oxidized AC with N,N’-bis[(triethoxysilyl)propyl]-1,2-cyclohexanediamine, followed by Pd2 complexation. The ICP result shows that the Pd2 loading capacity reached 0.79%. The samples were characterized by FT-IR, XPS and N2 adsorption-desorption. Diphenyl carbonate (DPC) was synthesized in a high pressure reaction vessel by oxidative carbonylation of phenol over the AC loaded Pd2 complex catalyst. The optimum operation conditions were determined as follows: reaction temperature of 100 ℃, reaction pressure of 7.0 MPa, reaction time of 5 h, and CH2Cl2 was used as solvent. The DPC yield reached 7.43% under the above conditions.

Abstract:Poly(divinylbenzene-co-diethyene glycol dimethacrylate) [P(DVB-DGD)] microspheres were prepared by precipitation polymerization in acetonitrile solvent with divinylbenzene-55 and diethyene glycol dimethacrylate as comonomers. FTIR、SEM and BET were applied to characterize P(DVB-DGD). FT-IR showed that two monomers copolymerized during the precipitation polymerization process. SEM indicated that no macroporous structure could be observed and the average number diameter of the monodisperese microspheres was 3.6 μm. The surface area and the average diameter of P(DVB-DGD) were 2.9 m2/g and 9.1 nm, respectively. With two samples as probes, the chromatographic performance of novel stationary phase packed with P(DVB-DGD) was evaluated by reversed-phase liquid chromatographic mode. The chromatographic results showed that the peak shape of the analytes was sharp and symmetry. The column exhibited high column efficiency and excellent chromatographic performance，which indicated that precipitation polymerization showed great potency of stationary phase used in HPLC.

Abstract:Abstract: Tuberose fragrance loaded monochlorotriazinyl-β-cyclodextrin(MCT-β-CD) nanoparticles were prepared by the inclusion complexation method. The effects of the volume ratio between athenol and water, the mass ratio between tuberose and MCT-β-CD, the reaction time , the stirring rate and the reaction temperature to the size distribution of tuberose fragrance-loaded MCT-β-CD nanoparticles were investigated. The tuberose fragrance-loaded MCT-β-CD were characterized by dynamic light scattering(DLS), Transmission electron microscope( TEM ), Infrared Spectrometer ( IR ) and Thermogravimetric Analyzer ( TGA ). Results showed that the particle size was 216.4 nm, the polydispersity index(PDI) was 0.221 and the fragrance loading capacity was 17.2% when v(CH3CH2OH): v(H2O) = 1:0.7, m(fragrance): m(Wall Materials) = 1:15, reaction time was 10 h, rotational speed was 1300rpm and reaction temperature was 35℃. The release rate of tuberose fragrance-loaded MCT-β-CD nanoparticles was decreased under the high temperature.

Abstract:Two new pentapeptides were totally synthesized using Leucine and Phenylalanine as starting materials, through changing cyclic sites and optimizing the route of synthesis. The yield of cyclization reation was nearly up to 50%. The products were purified by RP-HPLC, and the compound structures were characterized by 1H-NMR, 13C-NMR and MS.

Abstract:Activated carbon was loaded by TiO2 in gel state using sol-gel method, and then calcinated at 500℃ under the protection of nitrogen. TiO2/AC was characterized by BET ，scanning electron microscope (SEM) and XRD. Azithromycin wastewater was treated in a continuous flow photocatalytic reactor with ultraviolet lamp as light source and TiO2 / AC as catalyst. The results show that the azithromycin removal rate of the wastewater was not less than 94.1% under the conditions of load of in TiO2 / AC w(TiO2)=1.24%, pH = 4 and hydraulic retention time 90 min. After 240 hours continuous operation, the azithromycin removal rate differs little.

Abstract:A new nitrogen-free and phosphorus-free scale-inhibitor modified polyaspartic acid was synthesized in the water system. It contains hydroxyl, sulfonic acid groups and carboxyl groups. Explore the optimum synthetic condition as follows : the moles ratio of n (maleic acid): n (ammonia):n(citric acid): n-(2-amino-ethanesulfonic acid) is 1:2.8:0.12:0.075 ; reaction time is 3 hours; the thermal polycondensation temperature is 190℃; the polymerization time is 1 h.The product’s structure was characterized. A conclusion is drawn that scale inhibition rate of the agent was 82.9% when the dosage reaches on 24 mg／L .The new antiscalant is significantly better than the traditional productions.

Abstract:Employing the Pechmann method, with the acid catalyst, 7-hydroxy-4-methyl coumarin fluorescent whitening agent was synthesized by resorcinol and ethyl acetoacetate, through the dehydration condensation reaction. Then, the hindered amine light stabilizer 4-amion-2,2,6,6-tetramentylniperidine, coumarin type fluorescent brighteners and taurine were putted into the same molecular, with cyanuric chloride as crosslinking molecular, a new kind of yellowing inhibitor was synthesized. Using infrared spectrum characterized the structure of yellowing inhibitor, then, ultraviolet spectrum and fluorescence spectrum were employed to discuss its yellowing inhibition mechanism, and then, the application effect of the yellowing inhibitor was investigated through the Uv accelerated aging test. The results show that the yellowing inhibition effect of the new kind of yellowing inhibitor was better than the 7-hydroxy-4-methyl coumarin and 4-amion-2,2,6,6-tetramentylniperidine.

Abstract:The copolymer dispersant for ceramic powder PAA-AMPS was synthesized with acrylic acid and 2-acrylamido-2- methyl propane sulfonic acid as monomer, ammonium persulfate as redox initiator,and sodium hypophosphite as reducing agent. The effect of different reaction conditions on dispersing properties of copolymer has been investigated. The optimum conditions are as follows : the mole ratio of acrylic acid and 2-acrylamido-2- methyl propane sulfonic acid 8:1, the amount of initiator 1%, the amount of sodium hypophosphite 10%, the mass fraction of monomer 24%, reaction temperature 85℃. The copolymer was characterized and analyzed by FT-IR , GPC and TGA, and the effect of the concen tration of the copolymer（PAA-AMPS）on the viscosity of the ceramic slurry was investigated. The results show that smaller viscosity and better dispersion effects are achieved when the copolymer mass fraction is 0.25 %.

Abstract:N-Ethylethylenediamine was synthetized innovatively by using diethyl carbonate which was a green industrial chemical and ethylenediamine as raw materials．The effects of many factors were investigated for the reaction of N-alkylation，which included different catalysts (β zeolites, mordenites and Y zeolites)，Y zeolites modified by alkaline metals (Li, Na, K) and reaction conditions．The results show that Y zeolites have the best catalytic activity；It is proved that NaY zeolites have the best catalytic effect；under the conditions of reacting temperature 240℃，n（ethylene diamine）/n（diethyl carbonate）＝2，Weight Hourly Space Velocity for 15.8/ h and flowing rate of nitrogen for 120 mL/min，the N - ethyl ethylenediamine yield can reach up to 93.1%．

Abstract:The purpose of the study was looking for the novel compounds with biological activities. Based on the structure of the compounds with herbicidal activity, according to analogue synthesis, phenyl 3-chloropropanoate was synthesized using phenol and 3-chloropropanoyl chloride as starting materials by condensation reaction. Then 2-(4,6-dimethoxypyrimidin-2-yl)-8-(4,6-dimethoxypyrimidin-2-yloxy)-3,4-dihydroisoquinolin-1(2H)-one was synthesized by cyclization reaction, acylation reaction and substitution reaction respectively. The compound was confirmed by 1H NMR, MS and elemental analysis techniques.