Abstract:Biochar (BC) is widely used for activation of persulfate (PS) to remove difficult-to-degrade organic pollutants in water due to its good activation performance, low cost and environmental protection. Different modification methods can enrich the active sites on the surface of BC, further enhance the physicochemical properties of BC, and improve the activation performance and stability. This paper firstly reviewed the modification methods of biochar applied to activate PS, secondly summarized the reactive sites of BC activation of PS, the free radical and non-radical pathways of PS activation and their differences, and analyzed the modification and the effect of biomass feedstock on the transformation between the two different activation pathways, and finally looked forward to the development direction of BC activated PS application and mechanism research.

Abstract:Polymer microsphere is a kind of water-absorbable and swellable gel resin based on polyacrylamide, which has achieved good precipitation and oil-increasing effects in oil field profile control and flooding. As the mining focus gradually shifts to low permeability, medium low permeability and high temperature reservoirs, the particle size, slow swelling performance, temperature resistance, salt resistance and shear resistance of polymer microsphere have become important research topics. In this paper, the structure characteristics and structure-activity relationship of different polymeric microspheres in recent years were reviewed. The reservoir conditions applicable to different polymer microspheres were summarized, and the factors affecting the particle size and swelling performance of polymer microspheres were analyzed. The profile control and flooding mechanism of polymer microspheres was discussed, and the research direction of polymer microspheres was prospected: In order to solve the problems of polymer microspheres, such as the few reports about nanometer scale, the fast expansion rate at high temperature and the single displacement mechanism, it is necessary to deepen the research on the swelling mechanism and viscoelastic mechanism of polymer microsphere, and optimize the synthesis conditions of inverse microemulsion method, develop nanometer polymer microsphere with core-shell structure, and cooperate with other chemicals, so as to broaden the application field of polymer microspheres in low permeability, medium low permeability and high temperature reservoirs.

Abstract:The production of biochar from biogas digestate is one of the effective ways to achieve its safe disposal and resource utilization. The component structure and physicochemical properties of digestate-derived biochar are optimized to some extent with anaerobic digestion of digestate. Therefore, the digestate-derived biochar with low cost, wide source, good adsorption and catalytic properties is applied to remove pollutants from water. In this paper, the feedstock sources, preparation and modification methods of digestate-derived biochar are summarized. Besides, the current status of digestate-derived biochar as adsorbent or carbon-based catalyst in water treatment is discussed. In addition, the mechanism of pollutant removal by digestate-derived biochar is described. Finally, some problems and challenges of the application of digestate-derived biochar in water treatment is proposed, and the development direction of its application in aquatic environment is pointed out.

Abstract:3-methacrylamide propyl trimethyl ammonium chloride monomer (MAPTAC) is a kind of cationic quaternary ammonium salt monomer with high reactivity, temperature and pressure resistance and acid and alkali resistance, and salt resistance. The various polymers based on the MAPTAC have good application prospects. Firstly, the research progress of the synthesis method and process optimization of MAPTAC monomer and its polymers were introduced, respectively; Secondly, the typical examples of application research of MAPTAC polymers in daily chemical supplies, petroleum exploration, water treatment, medicine and other fields were listed. Finally, constructive opinions were put forward in developing of the MAPTAC polymer products with high relative molecular weight, serialized relative molecular weight and narrow relative molecular weight distribution, strengthening the research on the relationship between structure and performance and expanding the application fields of MAPTAC polymers.

Abstract:Polyimides have been widely used in many fields as a kind of functional polymer material with unique structure. Fluorinated polyimides have attracted more and more attention with the improvement of people's requirements on the comprehensive properties of material. The introduction of fluorine into polyimide structure can improve the solubility and transmittance and reduce the moisture absorption and dielectric constant of the material. The research progress in the molecular design, synthesis and application properties of fluorinated polyimides in recent years is reviewed. It is pointed out that structural design lead to the enhanced properties. Especially, the solubility, optical properties and thermal properties of fluorinated polyimides are summarized. And the development direction of their application in flexible display panel/substrate market is prospected.

Abstract:Total inorganic cesium lead halide perovskite (CsPbX3 (X=Cl、Br、I)) quantum dots have high stability, high color purity and high quantum yield, which has attracted wide attention. However, the toxicity of component lead in CsPbX3 quantum dots limits the further application of CsPbX3 quantum dots. Meanwhile, how to further improve its performance and stability also attract much attention. In this paper, a brief introduction of CsPbX3 quantum dots is presented. Furthermore, the research progress of selecting appropriate methods, including doping to control grain size and coating passivation to improve stability (coating agent, passivating agent, technical methods, etc.), is reviewed. Finally, the development direction of CsPbX3 quantum dots in the future is prospected.

Abstract:The plant honeysuckle extracts were used as reducing agent to prepare nano-zinc oxide and nano-silver, and then the cotton fabrics were treated with nano-zinc oxide alone, or further with nano-silver step by step to prepare multi-functional cotton-based textiles (ZnO-cotton fabric, ZnO/Ag-cotton fabric). The morphology and structure of cotton fabrics before and after finishing were analyzed by SEM, XRD and FTIR, and the versatility of cotton fabrics after finishing was discussed. The results showed that the distribution of nanoparticles on the cotton fabrics were relatively uniform and slightly agglomerated. Compared with ZnO-cotton fabric, the decomposition rates of ZnO/Ag-cotton fabric to methylene blue (MB) and red wine increased by 7.09% and 10.61%, respectively, indicating that nano-silver improved the photocatalytic activity of nano-zinc oxid. Although the adsorption amount of nano-particles in cotton fabrics decreased slightly after 10 times of washing, its decomposition rate to MB still reached more than 80%, indicating that the cotton fabrics has good self-cleaning ability and washing resistance performance after loading nanoparticles. In addition, the UV protection factor (UPF) values of ZnO-cotton fabric and ZnO/Ag-cotton fabric reached 33.23 and 41.06, respectively, and the antibacterial rates against E. coli and S. aureus reached more than 95%, showing excellent UV resistance and antibacterial properties.

Abstract:Cross-linked or linear poly-porphyrins were prepared via polycondensation of meso-tetra (4-carboxyphenyl)porphine or 4,4'-[10,20-bis(4-ethynylphenyl)porphyrin-5,15-diyl]dibenzoic acid and diamines with various chain-lengths as monomers. The relationship between the structure of poly-porphyrin with singlet oxygen yield was explored. The results indicated that when the number of carbon atoms in the flexible diamine was less than or equal to 4, the cross-linked poly-porphyrins exhibited higher singlet oxygen yield than the linear ones. On the contrary, the linear poly-porphyrins had more remarkable performance when the number of carbon atoms in the flexible diamine was larger than 4. The singlet oxygen yield of the cross-linked poly-porphyrins first increased and then decreased with the increase of the lengths of the carbon chains, while that of linear poly-porphyrins continuously increased. Moreover, the poly-porphyrins bearing the same charges on the end groups exhibited higher singlet oxygen yield. The singlet oxygen yield of the optimized poly-porphyrin was 2.37-fold that of the monomer.

Abstract:A two-photon fluorescence labelling probe LP was synthesized and characterized, and LP-Ag was obtained by LP labelling N-protein antigen (Ag) of SARS-COV-2, and LP-Ag was made into an immunochromatographic test strip (TPICS)/ kit (TPICK). Clinical applications showed that, in comparison with the nucleic acid method (PCR)/ the colloidal gold method, of TPICS positive coincidence rate (PR), negative coincidence rate (NR) and total coincidence rate (TR) were 98.73 % / 98.26 %, 98.76 % / 99.20 % and 98.75 % / 98.75 %, and the consistency coefficient kappa value (K) was 0.972 / 0.975, and sensitivity (SE), specificity (SP) and accuracy (AC) were 98.99 % / 98.10 %, 99.55 % / 99.53 % and 99.38 % / 99.06 %, respectively. Detection results of Detection reagent and reference reagents were consistent (K > 0.75) with no statistical difference. Dilute blood sample used for testing is generally 25~50 μL (Whole blood sample 5~10 μL), and the test period is within 10 min. It not only avoids the disadvantages of cumbersome nucleic acid operation and long detection period, but also overcomes the instability of colloidal gold due to the shedding of the adsorbed functional groups, and has good application value. LP-Ag can be used for SARS-COV-2 imaging in cells to identify negative and positive.

Abstract:A series of amide compounds have been prepared, using aliphatic or aromatic carboxylic acids and fatty amines as raw materials. A method for the direct amidation of carboxylic acids and amines with the participation of niobium pentachloride and ionic liquids has been established for the efficient preparation of amides. The influencing factors of reaction, such as the amount of catalyst, reaction solvent, reaction time and reaction temperature, were optimized. The results show that the yield of amidation reaction can reach 77-96% under the optimal reaction conditions (organic acid 2.0 mmol, organic amine 2.0 mmol, niobium pentachloride 0.16 mmol, 3-butyl-1-methyl-1H-imidazol-3-ium bromide 0.3 mmol, 4A M.S. 200 mg, toluene 4 mL, reaction temperature 110 oC, reaction time 24 h).

Abstract:Hydrogel is generally used as medical dressing because of its high water content and 3D network. However, it is a big challenge to achieve controllable drug release from the hydrogels. In order to prepare a kind of hydrogel dressing with good biocompatibility and controllable drug release, physical crosslinking was carried out. In this study, amino acid monomer N-acryl glycine amide (NAGA) and biological fermentation product itaconic acid (IA) were used as monomers. Under UV light, the hydrogel Poly(N-acryloylglycine-itaconic acid) (P(NAGA-IA)) could be formed without addition of crosslinking agent by self-polymerization. The obtained hydrogel showed lower sol-gel transition temperature (UCST), higher water swelling (40 times) and mechanical properties (540 kPa of maximum compression modulus), and better drug loading and release. NAGA chains provided intermolecular hydrogen bonds to give better comprehensive properties of hydrogels. Moreover, IA units provided pH stimuli responsive property, which could induce drug release. Therefore, the P (NAGA-IA) hydrogel could be used as wound dressing for wound healing.

Abstract:Polyethylene glycol monomethyl ether tartrate (TMPEG) was synthesized from tartaric acid and polyethylene glycol monomethyl ether (MPEG) without preprotection of hydroxyl group in tartaric acid by esterification reaction. A series of nonionic waterborne polyurethanes (TWPU) were prepared by the prepolymer process using the hydrophilic monomer as hydrophilic component. The successful synthesis and introduction of TMPEG were characterized by 1H-NMR, FTIR, TGA, tensile tests. The effects of quality score of hydrophilic monomer TMPEG on the storage stability, mechanical properties, water absorption of TWPU was studied. The results showed that when the mass fraction of TMPEG was 24% (based on the total mass of the prepolymer synthesized by the reaction of TMPEG, polyadipate -1,4-butanediol ester diol, isophorone diisocyanate, trimethylpropane, thylene diamine, the same below), the average particle size of TWPU emulsion was 85 nm, the contact angle, tensile strength, elongation at break of the TWPU film were 84°,7.9MPa, 768%, respectively. The comprehensive performance of TWPU film reached the best.

Abstract:The dopant-free hole-transporting materials are a key issue to realize the practical application of perovskite solar cells (PSCs). In this work, a black porphyrin molecule with high thermal stability and complete visible light absorption, 5,10,15,20-tetra[3,5-di(tert-butyl)phenyl]- β,β'-tetranaphthoquinone[6,7-g] zinc porphyrin (T1), was synthesized successfully and the studies of its photo physics, electrochemical properties and film-forming properties were carried out. Moreover, the highest occupied molecular orbital(HOMO) energy level of T1 is similar to that of spiro-OMeTAD, which can be well matched with the perovskite material MAPbI3. The power conversion efficiency (PCE) of the device based on T1 without any dopant can reach 13.43%, which was much higher than that of spiro-OMeTAD-based devices (11.63%) prepared under the same conditions.

Abstract:In this paper, P(NIPAm-AA-NMA) microgels were synthesized with N-isopropylacrylamide (NIPAm), acrylic acid (AA) and N-hydroxymethylacrylamide (NMA) by free radical emulsion polymerization. Then 4'-aminobenzo-18-crown-6 (ABC) decorated P(NIPAm-AA-NMA) microgels〔P(NIPAm-AABC-NMA)〕were prepared by using N-(3-dimethylaminopropyl)-N'-ethyl-carbodiimide hydrochloride (EDC) as condensation agent. Finally, the P(NIPAm-AABC-NMA) microgels self-assembled films were fabricated by the solvent evaporation method. The microstructure of microgels and self-assembled films were characterized by FTIR, SEM and DLS. Moreover, the temperature-sensitive properties of self-assembled films and their selective response to metal ions were investigated by UV-Vis. The results indicated that the particle size of the microgels before and after decoration by ABC was about 240 nm and 300 nm, respectively. With variation of environmental temperature or concentration of heavy metal ions, the particle size of the microgels in the self-assembled film changed accordingly, the incident light could be diffracted by the self-assembled film, and different structural colors of the film could be observed. In particular, when the Pb2+ concentration changes between 0 and 120 μmol/L, the red-shift of the self-assembled film diffraction peak was about 60 nm.

Abstract:In this study, low vacuum and room temperature plasma (LVRTP) was employed to pretreat Bacillus amyloliquefaciens CICC 10035. The optimal process conditions were screened by changing parameters including discharge power, treatment time and working pressure. The differential proteins were analyzed by bioinformatics using proteomics technology, and the effects of plasma pretreatment on cell growth and α-amylase secretion were discussed. The results showed that the optimal LVRTP pretreatment conditions were as follows: discharge power 120 W, treatment time 15 s, working pressure 135 Pa. Under the optimal conditions, α-amylase activity in the fermentation was more than 400 U/ml after 48 h, about 20% higher than the control. Proteomic analysis exhibited that LVRTP pretreatment had strong positive effects on protein synthesis and cell metabolism, especially in DNA repair and amino acid synthesis. On the one hand, LVRTP pretreatment improved the activity of cells and delayed the aging process; on the other hand, it promoted the synthesis and secretion of α-amylase in cells.

Abstract:Tannase was used to extract gallic acid from Coriaria nepalensis bark, and the extraction process was optimized by single factor and response surface experiments. The gallic acid extraction was purified and identified, and the antioxidant activity of the purified gallic acid was investigated and compared with the result of traditional acid extraction method. The experimental results show that when the amount of Coriaria nepalensis bark is used as the benchmark, the extraction yield of gallic acid can reach to10.79%±0.65% under the conditions of 20 u/g tannase addition in extraction pH 5 at 48 ℃ over 4 h. After purification by NKA-9 macroporous resin, the purity of gallic acid prepared by enzymatic method is 96.0%, which is higher than the purity of 81.3% prepared by acid extraction method. Its structure was characterized by 1HNMR, 13CNMR and heteronuclear singular quantum correlation (HSQC). Compared with acid extraction method, gallic acid prepared by enzymatic method has stronger antioxidant activity. When the mass concentration was 256 mg/L, the scavenging rate of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and hydroxyl radicals were 78.81% and 61.99%, respectively, and the reduction ability value of Fe3+ was 0.685.

Abstract:Cyanidin-3-O-glucoside (C3G) from black soybean hull was enzymatically acylated with lauric acid to achieve an anthocyanin derivative with improved lipophilic property. Various reaction solvent systems were tested and compared for the efficient acylation of anthocyanin by using crude black soybean hull extract (C3G content 35.8%), purified C3G sample (purity>80%), and C3G standard (purity>98%), respectively, as substrate. With the method developed, the acylation rate of the anthocyanin from crude black soybean hull extract reached 66.59%, which reached 75% of that from purified C3G; the acylated product, cyanidin-3-O-glucoside-lauric acid (C3G-La), reached a purity of 82.39% after simple liquid-liquid extraction, and further to a purity of 97.58% after separation and purification by normal phase silica gel. The stability test showed that C3G-La is more stable than C3G in either neutral or acidic pH environment, while both of them are labile under alkaline and light conditions.

Abstract:Polydopamine nanoparticles with mesoporous structure (MPDA NPs) were prepared by one-pot method using 1,3,5-trimethylbenzene as template, triblock copolymer PluronicF127 (EO106PO70EO106) as emulsion droplet stabilizer, ethanol as cosolvent and catalyst. Doxorubicin hydrochloride (DOX) was loaded by electrostatic adsorption and the nano drug delivery system was obtained by biomimetic camouflage of platelet membrane. The properties, morphology and particle size of the nanoparticles were characterized by transmission electron microscope, nano particle size analyzer, BET and UV spectrophotometer. The TEM results show that the surface of MPDA had a clear mesoporous structure, and the particle size of PLTM-DOX@MPDA nanoparticles coated by platelet membrane was about 184 nm. The BET results show that the pore size of MPDA was about 45 nm, the pore volume was 0.6232 m3/g, and the specific surface area was as high as 61.181 m2/g. The mesoporous structure supported MPDA as an efficient drug delivery system. The results of drug release in vitro showed that the nano drug delivery system had pH response to control drug release and could achieve sustained drug release. The results of cell uptake assay in vitro show that the nano drug delivery system could avoid phagocytosis of macrophages and actively target cancer cells. The results of cytotoxicity test in vitro showed that the nano-drug delivery system could enhance killing effect of DOX on MDA-MB-231 cells significantly.

Abstract:In order to reduce the odor of leather and improve its application performances, this study used zein, artemisia argyi essence (AAE) and Pluronic F127 as raw materials to prepare the emulsion of zein microcapsules loading AAE (AAE@ZMs) by anti-solvent method. Then AAE@ZMs emulsion and casein modified by caprolactam (Ca-Cpl) were blended to fabricate composite emulsion and then finish the leather. The results show that zein interacts with F127, AAE and glutaral through chemical cross-linking and hydrogen bonding. Meanwhile, F127 and AAE can rearrange the amino acids in zein and cause fluorescence quenching. The average particle size of AAE@ZMs is about 298.6 nm and the microcapsules have good dispersibility and stability. The encapsulation rate and loading rate of AAE@ZMs can reach 73.2% and 5.8% respectively, and the cumulative release rate is about 83.1% after releasing for 120 h. When AAE@ZMs were applied to the leather coating, the release cycle of AAE in the coated leather sample is 6 weeks. Moreover, the coated leather samples not only show good inhibitory effect on staphylococcus aureus and escherichia coli, but also possess better mechanical behaviors than that of the pristine leather.

Abstract:The reducing end of high amylose starch (HS) is modified with magnet particles by "Borch reduction -Click chemistry" to obtain modified starch with magnetic properties and prepare a regenerated starch film under the external magnetic field. The experiment includes the following steps， alkyne groups are introduced into unique reductive end of HS molecule, at the same time, Fe3O4 magnet nanoparticles(MNP) are coated with silane to obtain azidated magnet particles(azide-MNPs). Finally, the modified starch (MMS) with magnetic terminal is obtained through Click chemistry reaction. The successful formation of MMS was confirmed by XRD, FTIR, NMR and MALDI-TOF MS, etc. Furthermore, the mechanical properties of the regenerated starch film were tested, and the results showed that MMS gradually tended to be arranged in an orderly manner under the conditions of magnetic field induction. The resulting regenerated starch film had a increased breaking elongation and breaking strength, and improved short-range order. This study provides a new idea for the structural design and mechanical properties control of starch regeneration membranes based on an external magnetic field.

Abstract:In order to improve the selective adsorption, the cotton fiber was modified. First, polydopamine (PDA)-Fe3O4 magnetic cotton fiber was formed by polymerizing dopamine hydrochloride (DA) and nano-ferric oxide (Fe3O4) in Tris-HCl buffer solution. Secondly, dodecyltriethoxysilane (DTES) was used to further react PDA-Fe3O4 cotton fiber in alkaline ethanol aqueous solution to obtain DTES-PDA-Fe3O4 magnetic-superhydrophobic cotton fiber. FTIR, XRD, TG, SEM, EDS, AFM, water contact angle measuring instruments were used to characterize the chemical composition, surface microstructure, and hydrophobic properties of cotton fibers before and after modification. The separation efficiency, and adsorption properties also be tested. The results show that DTES-PDA-Fe3O4 cotton fiber had a rough structure of micro/nano size. The synthesized cotton fiber had magnetic with excellent superhydrophobicity and a water contact angle greater than 160°. It also had ultra-high selective adsorption, oil-water separation efficiency and reusability. It can absorb chloroform 8.96 times its own weight, and the separation efficiency of chloroform oil-water mixture could reach above 98.90%.

Abstract:Taking advantage of the temperature-increasing effect of inorganic molten salt hydrates, catalytic wet air oxidation of chloroacetic acid (CAA) wastewater under low pressures was conducted. The effects of catalyst type, reaction temperature and reaction time on the removal of CAA and COD were investigated. It was found that CuCl2 has the highest catalytic performance in dihydrate of CaCl2 among the tested catalysts. The removal rates of CAA and COD can reach up to 95% and 90% respectively. The free radical inhibition experiments and intermediate products analysis revealed that the catalytic oxidation mechanism is that CAA degrades to glycolic acid, formic acid and finally to CO2 and water in turns under the synergistic catalysis of hydroxyl free radicals that is generated by the interaction of oxygen with the catalyst cycle of Cu(Ⅱ)-Cu(Ⅰ)-Cu(Ⅱ).

Abstract:The aluminum sludge composite gel spheres adsorbent (AS-GEL) was prepared by using aluminum sludge, polyvinyl alcohol, sodium alginate as raw materials and sol-gel, freeze-drying as synthetic technology to adsorb Cr(VI) in the solution. The effects of solution pH, dosage of AS-GEL, initial concentration of Cr(VI) solution, temperature adsorption time, and the coexisting anion concentration on the adsorption of Cr(VI) were explored by static adsorption experiments. The mechanism was analyzed by SEM, FTIR, and XPS. The results showed that, when pH=4, AS-GEL dosage of 1.2 g/L, Cr(VI) initial concentration of 200 mg/L, temperature of 35℃, adsorption time of 120 min and no coexistence of other anions, the maximum adsorption capacity of Cr(VI) on AS-GEL was 73.364 mg/g. The order of coexisting anions is PO43- >NO3->Cl-. The adsorption of Cr(VI) by AS-GEL conformed to Langmuir isotherm adsorption models, Pseudo-first-order and Pseudo-second-order kinetic equations. The main adsorption mechanism is the electrostatic adsorption and reduction of Cr(VI) by the protonated group. Based on 5 adsorption-desorption experiments, the adsorption capacity remained 89.71% of the initial adsorption capacity. AS-GEL has the characteristics of low cost and easy solid-liquid separation, which has the prospect of engineering application.

Abstract:The double cross-linked network structure was formed by combining polyvinyl alcohol (PVA) and sodium alginate (SA) with boric acid (H3BO3) and calcium chloride (CaCl2), respectively. Potassium humate (KHA) and calcium-based montmorillonite (MMT) nanoparticles were loaded in it, so a double cross-linked gel beads (PVA/SA/KHA/MMT) were successfully prepared. The gel beads demonstrated excellent removal efficiency for methylene blue (MB) dye and Pb(Ⅱ). The physical and chemical properties of gel beads were systematically characterized by FTIR, XRD, TGA, SEM-EDS, zeta and BET. In addition, the adsorption process follows the pseudo-second-order kinetic model, and the experimental data was in good agreement with the Langmuir model. At 298 K, the maximum adsorption capacity (Qm) values of MB and Pb(Ⅱ) were 725.42 and 375.64 mg/g, respectively. The thermodynamic results showed that the adsorption process of the gel beads was spontaneous, endothermic, and driven by the increase of the overall entropy of the system. Meanwhile, the results of FTIR and XPS indicated that the adsorption mechanism of Pb(Ⅱ) was mainly through the chelation of carboxyl groups, while the adsorption of MB occurs through hydrogen bonding and electrostatic interaction. Furthermore, PVA/SA/KHA/MMT gel beads show excellent adsorption selectivity for MB and Pb(Ⅱ). Notably, it still showed a higher removal efficiency for (MB) and Pb(Ⅱ) after 5 cycles.

Abstract:An acrylate environmental adhesive was prepared by solution polymerization which used ethanol as solvent and N,N'-Methylenebisacrylamide(MBA) as crosslinking monomer,octadecyl acrylate as long-chain hydrophobic monomer,the NMR, IR, GPC, SEM, TGA and contact angle of the polymer were tested.Effects of reaction time,reaction temperature,crosslinking monomer and hydrophobic monomer on polymer,the optimal ratio of hard to soft monomer and the physical properties of the polymer film were studied.When reaction time was 4h,reaction temperature was 80 ℃,crosslinking monomer was 1 % (basd on the total mass of monomers,the same below),hard to soft monomer was 2:1~3:1,the molecular average weight of polymer was 12.86×104,thermal decomposition temperature was 309.3 ℃,glass transition temperature was 85.2 ℃ film,hardness reached to 4 H.With the addition of hydrophobic monomer,tensile strength and hydrophobicity of polymer film enhanced，when hydrophobic monomer was 3 %,tensile strength was 0.789 Mpa which improved 36.37 %,contact angle was 78.6 °,which improved 219.5 %.The prepared adhesive could be used for the solidification of sand soils and the fixation of sand panting，sand bottle drawing and relief painting for the effumability,fast permeability and no-pollution of ethanol.

Abstract:Abstract: We here reported a process for synthesis of avibactam sodium in kilogram scale by drug design. High purity oxalate was synthesized from L-pyroglutamic acid by esterification, tert-butoxycarbonyl protection, sulfur ylide ring opening, condensation of benzyloxyamine hydrochloride, de-tert-butoxycarbonyl, synthesis of piperidine ring, construction of the chiral carbon in position 5, isomer resolution. Oxalate gets avibactam sodium through ammonolysis, intramolecular urealization, debenzylation, sulfonic acid esterification, quaternary ammonium salt and sodium ion exchange reaction. The process not only involves mild reaction conditions, easy work-up methods, but also has a greener process. The total yield of avibactam sodium in kilogram scale was 19.7％, and HPLC purity 99.8％.

Abstract:Abstract: Using acenaphthene as raw material and NaBr/CeCl3.7H2O/H2O2 as bromination reagent, 5-bromoacenaphthene was obtained. Then it was nitrated with Al(NO3)3.9H2O/CH3COOH to synthesize 4-bromo-5-nitroacenaphthene. Finally, using cobalt acetate/manganese acetate/N-Hydroxyphthalimide (NHPI)/oxygen as oxidant, 4-bromo-5-nitro-1,8-naphthalene anhydride was prepared, which is an important intermediate of naphthalimide fluorescent dyes. The effects of raw material ratio, reaction temperature, reaction time, and solvent on the reaction yield were explored, and the optimal reaction conditions were obtained. For the bromination reaction, the temperature was 25 ℃, the reaction time was 3 h, the ratio of the amount of substances of acenaphthene, cerium chloride heptahydrate, and sodium bromide was 2∶1∶2.4, and the yield was 86.4%. For the nitration reaction, the temperature was 45 ℃, the reaction time was 8 h, the ratio of the amount of substances of 5-bromoacenaphthene, Al(NO3)3.9H2O was 1∶1.2, and the yield was 88.4%. For the oxidation reaction, the temperature was 110 ℃, the reaction time was 5 h, the ratio of the amount of substances of cobalt acetate, Manganese acetate, NHPI and 4-bromo-5-nitroacenaphthene was 1.2∶0.5∶1.2∶10, and the yield was 72.3%. A preliminary scale-up experiment was conducted by using this method. The reaction yield was still high after the reaction was expanded by 5-20 times. This method has the characteristics of cheap and readily available raw materials, mild and environmentally friendly reaction process, high product yield, and easy industrialization.

Abstract:3%Ru/CN was prepared via a simple ultrasound-assisted NaBH4 reduction method and used for hydrogenation of dimethyl terephthalate (DMT) to dimethyl 1,4-cyclohexanedicarboxylate (DMCD). The composition and surface properties of the support and catalyst were characterized by Raman spectrum, SEM, TEM, N2 adsorption-desorption isotherms, XRD, XPS, etc. The results showed that nitrogen was successfully incorporated into the carbon framework and the N-doped carbon material had a mesoporous structure. The effects of the amount of catalyst, reaction temperature, H2 pressure and reaction time on the hydrogenation of DMT to DMCD were investigated. Under optimal reaction conditions: m(DMT) is 1.00 g, m(catalyst) is 1.00 g, reaction temperature is 140 ℃,H2 pressure is 5.0 MPa and reaction time is 1h, the conversion of DMT is 100% and selectivity of DMCD is 99.3%. After recycled for 5 times, the catalytic performance of 3%Ru/CN-1000 catalyst did not decrease obviously, the conversion of DMT and the DMCD selectivity was 98.8% and 99.7%, respectively.