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第 36 卷第 2 期 精 细 化 工 Vol.36, No.2
201 9 年 2 月 FINE CHEMICALS Feb. 2019

丙烯酸系列化学品
水性抗菌羟基丙烯酸树脂的制备及性能

王若男 1,2 ，邹 滔 1,2 ，彭开美 1,2 ，周 曦 1,2 ，涂伟萍 1,2 ，胡剑青 1,2*

（1. 华南理工大学 化学化工学院，广东 广州 510640；2. 广东省绿色化学产品技术重点实验室，广东 广
州 510640）

摘要：以甲基丙烯酸甲酯（MMA）、丙烯酸丁酯(BA)、丙烯酸(AA)、丙烯酸羟丙酯(HPA)为单体，过氧化二苯
甲酰（BPO）为引发剂，乙醇为助溶剂，采用半连续溶液聚合法合成得到了水性羟基丙烯酸树脂（hs-WA），再
用三乙胺（TEA）中和，最后引入季铵盐抗菌剂 3-（甲氧基硅烷基）丙基二甲基十八烷基氯化铵（TSA），合成
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得到了水性抗菌羟基丙烯酸树脂（hs-WAT）。利用 FTIR、 HNMR、接触角、SEM、TG 和 DSC 对样品进行了分
析，并采用菌落计数法和抑菌圈法对样品进行了抗菌测试。结果表明：引入 TSA 反应后，树脂的表面形貌没有
改变；水接触角从 78.5增大至 87.5；样品的分解温度范围为 299~456 ℃，热稳定性提高；聚合物链柔韧性增
强（T g = 8.3 ℃）。抗菌性能分析表明：当引入 TSA 的质量分数为 4%（以树脂的固含量计）时，hs-WAT 膜对大
肠杆菌（革兰氏阴性菌）以及金黄色葡萄球菌（革兰氏阳性菌）的杀灭率达 99.9%以上，TSA 未发生迁移，合
成的聚合物为水性非渗透性接触型抗菌材料。
关键词：羟基丙烯酸树脂；TSA；抗菌聚合物
中图分类号：TQ322.4 文献标识码：A 文章编号：1003-5214 (2019) 02-0336-06

Preparation and Properties of Anti-bacterial
Waterborne Hydroxyl Polyacrylate

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1,2
1,2
1,2
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WANG Ruo-nan , ZOU Tao , PENG Kai-mei , ZHOU Xi , TU Wei-ping , HU Jian-qing 1,2*
（1. School of Chemistry and Chemical Engineering, South China University of Technology,Guangzhou 510640,
Guangdong, China; 2. Guangdong Provincial Key Laboratory of Green Chemical Technology, South China University of
Technology,Guangzhou 510640, Guangdong, China）
Abstract: Waterborne hydroxyl polyacrylate(hs-WA) was synthesized by semi-continuous solution
polymerization using methyl methacrylate(MMA),butyl acrylate (BA), acrylic acid (AA) and
hydroxypropyl acrylate (HPA) as monomers, benzoyl peroxide (BPO) as intiator, ethanol as co-solvent and
triethylamine (TEA) as neutralizer.Then, quaternary ammonium salt antibacterial agent, 3-(methoxysilyl)
propyldimethyloctadecyl ammonium chloride (TSA) was introducedand reacted with hs-WA to synthesize
an antibacterial waterborne hydroxy polyacrylate (hs-WAT).The samples were characterized by FTIR,
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HNMR, contact angle measurement, SEM, TG and DSC.Their antibacterial properties were tested by
colony counting method and inhibition zone method.The results showed that the introduction of TSA did
not change the surface morphology of hydroxyl polyacrylate, but made the water contact angle increase
from 78.5 to 87.5. The thermal properties of samples were enhanced and their decomposition
temperatures were between 299 ℃ and 456 ℃. In addition, the introduction of TSA improved the
polymer chain flexibility, the minimum glass transition temperature (T g) of samples was 8.3 ℃. When the
mass fraction of TSA was 4% based on the solid content of the resin, the as-prepared hs-WAT film could
eliminate over 99.9% of Gram-negative bacteria (E. coli) and Gram-positive bacteria (S.aureus) and no
inhibition zone formed, which indicated that TSA did not migrate and the synthesized hs-WAT was a
non-permeable contact antibacterial material.

收稿日期：2018-05-04; 定用日期：2018-09-28; DOI: 10.13550/j.jxhg.20180319
基金项目：广东省自然科学基金（2018A030313483）
作者简介：王若男（1994—），女，硕士生。联系人：胡剑青（1975—），男，副研究员，E-mial：glennhu@scut.edu.cn