Page 194 - 201902

·360· 精细化工 FINE CHEMICALS 第 36 卷

间体的合成方法。发现上述 Ugi-4CC 反应中，当酸 antimicrobial studies of 2, 4-dichloro-5-fluorophenyl containing
组件为邻位取代的苯甲酸时，反应活性较间位和对 thiazolotriazoles[J]. European Journal of Medicinal Chemistry, 2009,
44(2): 827-833.
位取代的苯甲酸低；提出其可能的原因是，脱 2,4- [11] Khay S, Choi J H, El-Aty A M A, et al. Dissipation behavior of
二甲氧苄基过程经历了一烯醇平面化过程，因邻位 lufenuron, benzoylphenylurea insecticide, in/on chinese cabbage
applied by foliar spraying under greenhouse conditions[J]. Bulletin of
苯甲酸取代基的空间效应，妨碍了平面化的进行。
Environmental Contamination and Toxicology, 2008, 81(4): 369-
372.
参考文献：
[12] Domling A, Wang W, Wang K. Chemistry and biology of
[1] Xu Xiaoyong (徐晓勇), Chen Gang (陈刚), Qian Xuhong (钱旭红). multicomponent reactions[J]. Chemical Reviews, 2012, 112(6):
Synthesis and bioactivities of novel substituted pyridinylmethylimino- 3083-3135.
thiazolidines and oxazolidines derivatives[J]. Agrochemicals (农药 [13] Gulevich A V, Zhdanko A G, Orru R V A, et al. Isocyanoacetate
化学学报), 2003, 5(1): 27-33. derivatives: synthesis, reactivity, and application[J]. Chemical Reviews,
[2] Liang Ying (梁英), He Hongwu (贺红武), Yang Ziwen (杨自文). 2010, 110(9): 5235-5331.
Progresses on research and development of the benzoylurea derivatives [14] Xu Wangjin(许望津), Chen Kaiyi(陈开义), Liu Jianbing(刘建兵).
[J]. Pesticide (农药), 2009, 48(9): 625-628. Synthesis and biological activity of diamide compounds containing
[3] Wan Peihong (万培红), Sun Li (孙丽), Guo Xiuli (郭秀丽). The 5-aminothiazole ring [J]. Fine Chemicals(精细化工), 2018, 35(4):
research progress of new crop pesticides[J]. Journal of Anhui 645-651.
Agricultural Sciences (安徽农业科学), 2014, 42(14): 4260-4264. [15] Wang S, Allan R D, Skerritt J H, et al. Development of a class-
[4] Zhang Xinfei (张新飞). The synthesis and biological activity of the specific competitive ELISA for the benzoylphenylurea insecticides
new chloring amide compounds[D]. Qingdao：Qingdao University of [J]. Journal of Agricultural and Food Chemistry, 1998, 46(8): 3330-
Science and Technology (青岛科技大学), 2014. 3338.
[5] Yang Tingting (杨亭亭). Synthesis of N-acyl cyclourea derivatives [16] Li Ying (李映), Zi Ning (紫宁), Hu Jun (胡君). Studies on chitin
and ionic compounds with potential pesticide activity[D]. Shanghai： synthase inhibitors[J]. Progress in Chemistry, 2007, 19(4): 535-543.
East China Normal University (华东师范大学), 2012. [17] Kennedy A L, Fryer A M, Josey J A. A new resin-bound universal
[6] Brock T, Roessink I, Belgers J D M, et al. Impact of a benzoyl urea isonitrile for the Ugi 4CC reaction: Preparation and applications to
insecticide on aquatic macroinvertebrates in ditch mesocosms with the synthesis of 2, 5-diketopiperazines and 1, 4-benzodiazepine-2, 5-
and without non-sprayed sections[J]. Environmental Toxicology and diones[J]. Organic Letters, 2002, 4(7): 1167-1170.
Chemistry, 2009, 28(10): 2191-2205. [18] Ilyin A, Kysil V, Krasavin M, et al. Complexity-enhancing
[7] Hantzsch A, Weber J H. Ueber verbindindungen des thiazols acid-promoted rearrangement of tricyclic products of tandem Ugi
(pyridins der thiophenreihe)[J]. Berichte Der Deuschen Chemischen 4CC/intramolecular Diels-Alder reaction[J]. Journal of Organic
Gesellschaft, 1887, 20(2): 3118-3132. Chemistry, 2006, 71(25): 9544-9547.
[8] Briner P H, Fyfe M C T, Martin P, et al. Practical synthesis of 2- [19] He P, Nie Y B, Wu J, et al. Unexpected synthesis of indolo [1, 2-c]
amino-5-fluorothiazole hydrochloride[J]. Organic Process Research quinazolines by a sequential Ugi 4CC–staudinger–aza-wittig–
& Development, 2006, 10(2): 346-348. nucleophilic addition reaction[J]. Organic & Biomolecular Chemistry,
[9] Kane J J L, Hirth B H, Liang B, et al. Ureas of 5-aminopyrazole and 2011, 9(5): 1429-1436.
2-aminothiazole inhibit growth of gram-positive bacteria[J]. Bioorganic [20] Luo Jilong (罗纪龙), Liu Jianbing (刘建兵). Synthesis of 2, 4-
& Medicinal Chemistry Letters, 2003, 13(24): 4463-4466. disubstituted-5-aminothiazoles based on the Ugi-4CC reaction[J].
[10] Karthikeyan M S. Synthesis, analgesic, anti-inflammatory and Fine Chemical Intermediates (精细化工中间体), 2017, 47(6): 21-24.