Page 69 - 《精细化工》2022年第9期

第 9 期 李培英，等: 萃取非甾体抗炎药物材料的制备及性能 ·1787·

由表 5 可知，该方法对目标化合物的回收率在 non-steroidal anti-inflammatory drugs from waste water samples by
80%以上，SD≤5.1%，线性范围在 10~1000 μg/L，检 rotating-disk sorptive extraction[J].Talanta, 2014, 128: 486-492.
[10] United States Environmental Protection Agency. Determination of
出限和定量限分别为 0.02~0.10 μg/L 和 0.07~0.33 μg/L， pharmaceuticals and personal care products in drinking water by
低于文献报道的超支化大容量混合阴离子交换固相萃 solid phase extraction and liquid chromatography electrospray
取柱检出限（4~9 μg/L）和定量限（5~33 μg/L） [12] 。 ionization tandem mass spectrometry (LC/ESI-MS/MS): Method
542[S]. Washington, D.C: United States, 2016.
[11] WANG Y K, OU Y H, XIE S Y, et al. Magnetic graphene solid-phase
3 结论 extraction for the determination of 47 kinds of non-steroidal anti-
inflammatory drug residues in animal food with liquid chromatography
（1）本研究以 1,6-己二胺、乙二醛和甲醛为原 tandem mass spectrometry[J]. Food Analytical Methods, 2019, 12(6):
料、醋酸为阴离子、水为溶剂，60 ℃下成功制备了 1346-1368.
[12] HUANG C N, LI Y, YANG J J, et al. Hyperbranched mixed-mode
PAIL，且 PAIL 已成功涂覆在 Oxi-CFP 上，制备出 anion-exchange polymeric sorbent for highly selective extraction of
成本低廉的萃取纸。 nine acidic non-steroidal anti-inflammatory drugsfrom human urine[J].
（2）制备的萃取纸可用于水中 NSAIDs 的富集 Talanta, 2018, 190: 15-22.
[13] GILART N, MARCE R M, FONTANALS N, et al. A rapid
浓缩。当 PAIL 制备温度为 60 ℃时且 PAIL 的质量 determination of acidic pharmaceuticals in environmental waters by
分数为 5%时，制备的萃取纸对 4 种 NSAIDs 的吸附 molecularly imprinted solid-phase extraction coupled to tandem mass
2
2
量，分别为 80.4 ng/cm （托美汀）、76.3 ng/cm （酮 spectrometry without chromatography[J]. Talanta, 2013, 110: 196-201.
[14] DAHANE S, GARCIA M D G, BUENO M J M, et al. Determination
2
2
洛芬）、103.0 ng/cm （萘普生）、122.0 ng/cm （双 of drugs in river and wastewaters using solid-phase extraction by
氯芬酸）。 packed multi-walled carbon nanotubes and liquid
（3）建立了萃取纸与 HPLC-MS/MS 联用萃取 chromatography-quadrupole-linear ion trap-mass spectrometry[J].
Journal of Chromatography A, 2013, 1297: 17-28.
检测水中 4 种 NSAIDs 的方法，加标回收率均> [15] MASHKURAH A R, IBRAHIM W A W, RAMLI Z, et al. New
80%、检出限和定量限分别为 0.02~0.10 μg/L 和 sol-gel hybrid material in solid phase extraction combined with liquid
0.07~0.33 μg/L。 chromatography for the determination of non-steroidal anti-
inflammatory drugs in water samples[J]. Chromatographia, 2016,
79(7/8): 421-429.
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