Page 195 - 《精细化工》2023年第4期

す 4 ᱌ ᑍచచ喑ぶ: ✂叓 ȕ-㦎㖇㈃-䚗㯸⮪-⢶ㆠ䚴⏣㯸⮪㏠ㆠㆿၽ⮱ݣิࣷڣ䉌䒪 Į-⶘䓈䚥 g881g

ㆿၽܳ᪐⋟⮱ pH ͧ 2.0~8.0喑⩕㏠ㆠ⓭ٶㆿᏓЗ≸ ㏠ㆠㆿၽܳ᪐⋟⮱⚔❴ȡϻఫ 1 जВⰸܧ喑ᒀ
䄂㏠ㆠㆿၽܳ᪐⋟⮱ㆿᒱȠZata ⩢ѺȠ็ܳ᪐㈨᪝ m(Zein)ńm(MC)=1ń0.6 ᬣ喑ݣิ䓴⼸͚๔䛼㯸⮪
喍PDI喎ౕ̺ह pH ̸⮱अࡃᗲۢȡ⃼͗ᵤ৮䛺ฺ 3 ⁎ȡ ⳙ䬡㖇䯳↶䭺喑ౕᏂ䘕ᒏ᜽๔䛼叱㞟↶⋭喑ㆿᒱᬍ
1.3.2.3 ⻨ၽᑧᏓ⽠Ⴧᕔ⮱≸䄂 ∂≸䛼ȡᒀ m(Zein)ńm(MC)=1ń1.2 ᬣ喑ݣิ䓴⼸
ᄳ⊀Ꮣͧ 0Ƞ2.5Ƞ5Ƞ10Ƞ15 mol/L ⮱ NaCl ⏣ ͚Όܧ⣝㯸⮪㊛⟣➖Ꭳ́㑀ᚏ↶⋭ȡᒀ m(Zein)ń
⋟ߍڒݝ 50 mL M9 ㏠ㆠܳ᪐⋟͚喑Ҭ㏠ㆠㆿၽܳ m(MC)=1ń1.8 ᬣ喑ݣิ䓴⼸͚ᒏ᜽⮱ܳ᪐Ҁ̺⽠
᪐⋟͚⮱ NaCl ᰭ㏵⊀Ꮣܳݘͧ 0Ƞ50Ƞ100Ƞ200 Ⴧ喑ౕბ⍖̸ᩫ㒛܍ܳ䧌ऻღகᏂ䘕ܧ⣝ᄼ⮱ఏ㖇
হ 300 mmol/Lȡ≸Ⴧ᫦∂ह 1.3.2.2 㞯ȡ Ҁȡᒀ m(Zein)ńm(MC)=1ń2.4~1ń3.6 ᬣ喑ᒏ᜽⮱
1.3.2.4 ⍖Ꮣ⽠Ⴧᕔ⮱≸䄂 ㏠ㆠㆿၽܳ᪐⋟᭜⽠Ⴧ́౴̭⮱喑⇎ᰶ↶⋭ȡ䔆ज
ः 5 mL ᫝凉ݣิ⮱ M9 ㏠ㆠㆿၽܳ᪐⋟䒙⼨㜠
㘪᭜ౕࣺ⏣ݯ䓴⼸͚ MC ᐭ໸॥䭱ౕ Zein 㶕䲏喑ϻ
ڤඋ䄂ノ͚喑ܳݘౕ 40Ƞ50Ƞ60Ƞ70Ƞ80Ƞ90 Ď
㔹ᒏ᜽⽠Ⴧ⮱㏠ㆠㆿၽ喑ᒀ MC ⩕䛼䓴ѻᬣ喑ᄾ䛼
̸Ⅱ⊡ߍ☚ 30 min喑♣ऻ侙̷۝⊡喍0 Ď喎10 min喑 㶕䲏ፓ䉌⩢㢤⮱㖇व➖̺䋠В⽠Ⴧ㏠ㆠㆿၽ㶕䲏⮱
ᰭऻᄳᵤ৮ᩫ㒛λ 4 Ď۝マ͚וႅ 12 hȡ≸Ⴧ᫦∂
䘕ܳₐ⩢㢤喑ㆿၽ䬡⮱ᢿ᫒߈䭺ѻ喑ᄩ㜡㏠ㆠㆿၽ
ह 1.3.2.2 㞯ȡ
↶⋭ȡ
1.4 Ҁใ⊵ࡃ὎᠌჋侹
὎᠌㗰⋟⮱䙺ݣ喟ᄳ 7 mL ⊀⯽䚥Ƞ2.0 g NaClȠ
3.2 g 㗰㯸⮪䚣⏣λ 250 mL ࣨ⻨ၽⅡ喑♣ऻ⩕
1.0 mol/L ⯽䚥䄰᪡ pH 㜠 1.2喑⩕ࣨ⻨ၽⅡჇღ㜠
1000 mLȡ
὎᠌㗍⋟⮱䙺ݣ喟ᄳ 8.1 g ⸤䚥ι⅏䧍Ƞ1.8 g
NaOHȠ5.2 g ⡗㗳⯽Ƞ4.8 g 㘝㯸⮪䚣ߍڒࣨ⻨ၽⅡ
͚喑Ⴙڕ⏣㼐⌤࠭ऻ喑⩕ 0.1 mol/L NaOH ⏣⋟䄰᪡
pH 㜠 7.0喑♣ऻ⩕ࣨ⻨ၽⅡჇღ㜠 1000 mLȡ
὎᠌㗰⊵ࡃ喟ः 10 mL M9 ㏠ㆠㆿၽܳ᪐⋟হ

10 mL ὎᠌㗰⋟ᩫڒݝⰥᄦܳၽ䉕䛼ͧ 8000 ⮱䔼Ჽ
㶸͚喑ិ䔼Ჽ㶸ᩫڒݝⰈᰶ 200 mL ὎᠌㗰⋟⮱☔Ნ a—m(Zein) ń m(MC)=1 ń 3.6 喠 b—m(Zein) ń m(MC)=1 ń 3.0 喠
c—m(Zein) ń m(MC)=1 ń 2.4 喠 d—m(Zein) ń m(MC)=1 ń 1.8 喠
͚喑ౕ 37 ĎⅡ⊡͚⊵ࡃ 2 hȡܳݘౕࣺᏁ 0Ƞ30Ƞ
e—m(Zein)ńm(MC)=1ń1.2喠f—m(Zein)ńm(MC)=1ń0.6
60Ƞ90Ƞ120 min ᬣःܧ 1 mL ⊵ࡃ⋟喑हᬣाڣ͚ ఫ 1 ̺ह Zein হ MC 䉕䛼℁ݣิ⮱ Zein-MC ㏠ㆠㆿၽ
㶒ߍ 1 mL ᫝凉὎᠌㗰⋟喑⊵ࡃ⋟–20 Ďוႅิ⩕ȡ ܳ᪐⋟⮱⚔❴
὎᠌ᄼ㗍⊵ࡃ喟ᄳ 2 h ὎᠌㗰⊵ࡃऻ⮱⊵ࡃ⋟ Fig. 1 Photos of Zein-MC nanoparticles dispersions prepared
20 mL ߍڒݝ 5 mL ὎᠌㗍⋟͚喑ិ䔼Ჽ㶸ᩫڒݝⰈ with different mass ratio of Zein to MC

ᰶ 200 mL ὎᠌㗍⋟⮱☔Ნ͚喑ౕ 37 Ď⮱Ⅱ⊡͚⊵ ఫ 2 ͧ Zein হ MC 䉕䛼℁ᄦ Zein-MC ㏠ㆠㆿၽ
ࡃ 2 hȡܳݘౕࣺᏁ 30Ƞ60Ƞ90Ƞ120Ƞ150Ƞ180Ƞ
⮱ㆿᒱহ PDI ⮱ᒞ৺喑⩞λ M1ȠM2 ᒏ᜽↶⋭ᬍ∂
210Ƞ240 min ᬣःܧ 1 mL ⊵ࡃ⋟喑हᬣाڣ͚㶒
≸䛼喑ₑั̺ں䃕䃧ȡ
ߍ 1 mL ᫝凉὎᠌㗍⋟喑⊵ࡃ⋟–20 Ďוႅิ⩕ȡ
LA ⮱㉜⼜䛷ᩫ⢴ᠶᐼ喍4喎䔈㵹䃎ツ喟
n 1
V ¦ U i V U 0 n
R /% n u 100 喍4喎
m
ᐼ͚喟R ͧ LA ⮱㉜⼜䛷ᩫ⢴喑%喠V ͧ⃼⁎ःᵤ
⮱Ҁ⼜喑L喠 ȡ i ͧ⃼⁎ःᵤ LA ⮱䉕䛼⊀Ꮣ喑mg/L喠
ȡ n ͧす n ⁎ःᵤ LA ⮱䉕䛼⊀Ꮣ喑mg/L喠V 0 ͧ὎᠌
䛷ᩫ⋟⮱Ҁ⼜喑L喠m ͧᵤ৮͚क़ᰶ⮱ LA 䉕䛼喑mgȡ

2 㐀᳉̻䃕䃧

ఫ 2 Zein হ MC 䉕䛼℁ᄦ Zein-MC ㏠ㆠㆿၽㆿᒱহ PDI
2.1 Zein হ MC ⮱䉕䛼℁ᄦ Zein-MC ㏠ㆠㆿၽ⮱
⮱ᒞ৺
ᒞ৺ Fig. 2 Effects of mass ratio of Zein to MC on particle size
ఫ 1 ̺ͧह Zein হ MC 䉕䛼℁ݣิ⮱ Zein-MC and PDI of Zein-MC nanoparticles