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第 9 期 张孜文,等: UV 固化 PHMG 基抗菌非离子水性聚氨酯的制备与性能 ·1805·
细菌繁殖,聚合物形成的薄膜会切断微生物的呼吸 Biologically active polymers. Ⅴ . Synthesis and antimicrobial
activity of modified poly(glycidyl methacrylate-co-2-hydroxyethyl
通道,使其迅速窒息、死亡 [23] ;聚乙二醇与 MPHMG methacrylate) derivatives with quaternary ammonium and
的协同作用使得胶膜表面的细菌被快速杀死。 phosphonium salts[J]. Journal of Polymer Science Part A Polymer
Chemistry, 2010, 40(14): 2384-2393.
[6] JANG J, KIM Y. Fabrication of monodisperse silica-polymer
core-shell nanoparticles with excellent antimicrobial efficacy[J].
Chemical Communications, 2008, 34(34): 4016-4018.
[7] XU D Q, SU Y L, ZHAO L L, et al. Antibacterial and antifouling
properties of a polyurethane surface modified with perfluoroalkyl
and silver nanoparticles[J]. Journal of Biomedical Materials Research
Part A, 2017, 105(2): 531-538.
[8] WEI D F, MA Q X, GUAN Y, et al. Structural characterization and
antibacterial activity of oligoguanidine (polyhexamethylene guanidine
hydrochloride)[J]. Materials Science & Engineering C-Materials for
Biological Applications, 2009, 29(6): 1776-1780.
[9] LI P, SUN S Y, DONG A, et al. Developing of a novel antibacterial
图 8 GNWPU 胶膜的抗菌机理 agent by functionalization of graphene oxide with guanidine polymer
Fig. 8 Antibacterial mechanism of GNWPU film with enhanced antibacterial activity[J]. Applied Surface Science,
2015, 355: 446-452.
[10] LIU M, YU D, XU X, et al. Endowing recyclability to anti-adhesion
3 结论 materials via designing physically crosslinked polyurethane[J].
Journal of Materials Chemistry A, 2019, 7, 22903-22911.
(1)利用 GMA 中环氧基与 PHMG 端氨基的环 [11] LIU M H, LIU F H, XU X B, et al. Coexistence of anti-adhesion
performance, intrinsic stretchability, and transparency[J]. ACS
氧开环反应制备了 MPHMG,MPHMG 中 GMA 与 Applied Materials & Interfaces, 2019, 11(18): 16914-16921.
PHMG 的物质的量比为 1.6∶1.0,>1.0∶1.0;采用 [12] XU J C, RONG X S, CHI T Y, et al. Preparation, characterization of
UV-curable waterborne polyurethane-acrylate and the application in
紫外固化技术将 MPHMG 键合到非离子水性聚氨酯
metal iron surface protection[J]. Journal of Applied Polymer Science,
的交联网络中,制备了可以长效抗菌的 GNWPU 材料; 2013, 130(5): 3142-3152.
[13] YUAN C D, WANG J P, CUI M T, et al. Aqueous PUA emulsion
(2)胶膜中 MPHMG 的存在会增加聚氨酯软段
prepared by dispersing polyurethane prepolymer in polyacrylate
的氢键作用和亲水基团的含量,使 GNWPU 胶膜的 emulsion[J]. Journal of Applied Polymer Science, 2016, 133(11):
热稳定性、力学性能和吸水率均有所提高,胶膜 43203-43212.
[14] XU H P, QIU F X, WANG Y Y, et al. UV-curable waterborne
GNWPU2.0 相对于胶膜 NWPU,其 T 30% 和 T 50% 分别 polyurethane- acrylate: Preparation, characterization and properties[J].
提高了 7.3 和 12.6 ℃,拉伸强度提高了 1.6 MPa, Progress in Organic Coatings, 2012, 73(1): 47-53.
[15] CHEN F Y (陈飞燕), LI Z L (李宗亮), CHEN J (陈洁), et al.
吸水率增加了 6.8%; Preparation of polyurethane coating bonded with guanidinium oligomer
(3)抗菌测试表明,MPHMG 已经成功键合到 and their antibacterial and mould-proof performance[J]. Journal of
Founctional polymers (功能高分子学报), 2017, 30(3): 333-340.
聚氨酯的分子链中,当胶膜中 MPHMG 的含量大于 [16] SAHRARO M, YEGANEH H, SORAYYA M. Guanidine hydrochloride
1.0%时,接触细菌 2 h,对金黄色葡萄球菌和大肠杆 embedded polyurethanes as antimicrobial and absorptive wound
dressing membranes with promising cytocompatibility[J]. Materials
菌的抗菌率均可以达到 99.8%以上。 Science & Engineering C-Materials for Biological Applications,
(4)PHMG 改性非离子水性聚氨酯取得了很好 2016, 59: 1025-1037.
[17] WANG Y C (王永超), LING S D (林树东), TU Y Y (涂园园), et al.
抗菌效果,未来应该将 PHMG 的应用扩展到离子型 Synthesis and properties of a novel bis-phenylbiguanide as latent-
水性聚氨酯体系,而如何在引入 PHMG 之后保证离 curing agent for epoxy resin[J]. Fine Chemicals (精细化工), 2016,
33(2): 224-230.
子型水性聚氨酯乳液的稳定性是需要解决的首要 [18] WEI D F, ZHOU R H, GUAN Y, et al. Investigation on the reaction
问题。 between polyhexamethylene guanidine hydrochloride oligomer and
glycidyl methacrylate[J]. Journal of Applied Polymer Science, 2013,
参考文献: 127(1): 666-674.
[19] SHI X, SHI H X, WU H K, et al. A novel fluorinated diamine as an
[1] FUCHS A D, TILLER J C. Contact-active antimicrobial coatings extender for polyurethanes[J]. Chemical Papers, 2018, 72(5): 1-10.
derived from aqueous suspensions[J]. Angewandte Chemie-International [20] ZENG P (曾平), XIE W Y (谢维跃), JIANG J (蒋健), et al. Study on
Edition, 2006, 45(40): 6759-6762. synthesis of polyhexamethylene guanidine hydrochloride[J]. China
[2] KUMAR M, BALA R, GONDIL V S, et al. Combating food Surfactant Detergent & Cosmetics (日用化学工业), 2015, 45(11):
pathogens using sodium benzoate functionalized silver nanoparticles: 629-631.
Synthesis, characterization and antimicrobial evaluation[J]. Journal [21] HO C H, TOBIS J, SPRICH C, et al. Nanoseparated polymeric
of Materials Science, 2017, 52(14): 8568-8575. networks with multiple antimicrobial properties[J]. Advanced Materials,
[3] ZHANG Z W (张孜文), YANG J J (杨建军), WU Q Y (吴庆云), et 2010, 16(12): 957-961.
al. Latest research progress of antibacterial polyurethane coating[J]. [22] MATTHEIS C, WANG H, MEISTER C, et al. Effect of guanidinylation
New Chemical Materials (化工新型材料), 2019, 47(8): 9-12. on the properties of poly(2-aminoethylmethacrylate)- based antibacterial
[4] WASCHINSKI C J, ZIMMERMANN J, SALZ U, et al. Design of materials[J]. Macromolecular Bioscience, 2013, 13(2): 242-255.
contact-active antimicrobial acrylate-based materials using biocidal [23] WANG X W, LU P, LI Y, et al. Antibacterial activities and
macromers[J]. Advanced Materials, 2010, 20(1): 104-108. mechanisms of fluorinated graphene and guanidine-modified graphene[J].
[5] KENAWY E R, ABDEL-HAY F I, EL-SHANSHOURY E R R, et al. RSC Advances, 2016, 6(11): 8763-8772.