Page 125 - 《精细化工》2022年第10期

第 10 期 袁 帆，等: 黏膜黏附性缺氧响应型壳聚糖胶束的制备与性能 ·2059·

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图 7 CS-NID 8.9 在常氧和缺氧条件下的紫外光谱（a）； [10] ZHANG B (张蓓), CHANG B S (常柏松), SUN T L (孙涛垒).
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nanoparticles as a promising tool in nanomedicine with particular
性 ，可实现 对 DOX 的 高效装 载。载药 的 emphasis on oncological treatment[J]. Cancer Cell International,
DOX@CS-NID 胶束在正常生理条件下，DOX 最大 2021, 21 (1): 318-339.
释放量仅为 42%。而在缺氧酸性条件下由于硝基咪 [16] SOGIAS I A, WILLIAMS A C, KHUTORYANSKIY V V. Why is
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2 h 内释放量高达 65%，24 h 内释放量超过 92%。
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疗缺氧相关疾病。
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