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·1102·                            精细化工   FINE CHEMICALS                                  第 36 卷

            结果见图 8。如图 8 所示,随着 SP-Fe(Ⅲ)浓度逐                      参考文献:
            渐增加,SI 呈现先增加后逐渐下降趋势;当质量浓                           [1]   Tang  M,  Wang  D,  Hou  Y,  et al.  Preparation,  characterization,
                         –3
            度为 31.25×10 g/L 时,与 SP 相比,SP-Fe(Ⅲ)对                    bioavailability  in vitro  and  in  vivo  of  tea  polysaccharides–iron
            淋巴细胞增殖提高了 44.35%。说明 SP-Fe(Ⅲ)具                          complex[J]. European Food Research and Technology, 2013, 236(2):
                                                                   341-350.
            有较高的免疫保护活性。
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                                                                   hepcidin  and  reduces  iron  overload  in  mice  via  activation  of  p38
                                                                   mitogen-activated  protein  kinase[J].  Biochemical  and  Biophysical
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                                                               [4]   Chen H W,  Yang T S,  Chen M J,  et al.  Purification  and
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            图 7    SP-Fe(Ⅲ)在人工模拟胃肠液中释放 Fe(Ⅲ)质                      2001, 56(5/6/7): 497-500.
                  量分数变化情况                                      [6]   Kurd  F,  Samavati  V.  Water  soluble  polysaccharides  from  Spirulina
            Fig. 7    Mass fraction change of Fe (Ⅲ) release from SP-Fe  platensis: Extraction and in vitro anti-cancer activity[J]. International
                   (Ⅲ)  in  artificial  gastric  juice  (pH  2.0)  and   Journal of Biological Macromolecules, 2015, 74: 498-506.
                   artificial intestinal juice (pH 6.8) with time   [7]   Chaiklahan  R,  Chirasuwan  N,  Triratana  P,  et al.  Polysaccharide
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                                                                   polysaccharides  of  Arthrospira  (Spirulina) platensis  induce  the
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                                                                   anthracene[J]. Oral Oncology, 2008, 44(10), 956-962.

                                                               [11]  Cui J, Li Y, Yu P, et al. A novel low molecular weight Enteromorpha
               图 8    不同浓度下 SP 和 SP-Fe(Ⅲ)对 SI 的影响                  polysaccharide-iron  (Ⅲ)  complex  and  its  effect  on  rats  with  iron
            Fig. 8    Effect of SP and SP-Fe(Ⅲ)  on the SI at different   deficiency  anemia  (IDA)[J].  International  Journal  of  Biological
                   concentrations                                  Macromolecules, 2018, 108: 412-418.
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            3    结论                                                lymphocyte  proliferation  and  complement  fixing  activities[J].
                                                                   International  Journal  of  Biological  Macromolecules,  2018,  108:
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                 在制备 SP-Fe(Ⅲ)基础上,采用红外光谱、
                                                               [13]  Viteri F E,  Casanueva  E, Tolentino  M  C,  et al.  Antenatal  iron
            差示扫描量热分析、热重分析、X 射线衍射和扫描                                supplements consumed daily produce oxidative stress in contrast to
            电镜对其性质及结构进行了表征;对其抗氧化及淋                                 weekly  supplementation  in  Mexican  non-anemic  women[J].
            巴细胞增殖活性进行了综合分析。                                        Reproductive Toxicology, 2012, 34(1): 125-132.
                                                               [14]  Torino A B B, Gilberti M F P, Costa E, et al. Evaluation of red cell
                 (1)制备 SP-Fe(Ⅲ)中 Fe(Ⅲ)质量分数为
                                                                   and  reticulocyte  parameters  as  indicative  of  iron  deficiency  in
            16.42%± 1.17%;与 SP 相比,SP-Fe(Ⅲ)具有较高                     patients  with  anemia  of  chronic  disease[J].  Revista  Brasileira  de
            的抗氧化活性。                                                Hematologia e Hemoterapia, 2014, 36(6): 424-429.
                 (2)在模拟人工胃肠液条件下,SP-Fe(Ⅲ)                       [15]  Zhu  Jie  (朱劼),  Ren  Shuzhen  (任淑振),  Peng  Jiangchen  (彭江晨).
            释放出的 Fe(Ⅲ)质量分数达到 83.64%。                               Optimization of polysaccharide extraction polysaccharide cell freeze-
                                                                   thaw  cooperated  with  hot  water  extraction  and  deproteinization[J].
                 (3)SP-Fe(Ⅲ)具有较高的免疫保护作用和                           Food Science (食品科学), 2012, 33(24): 111-116.
            较好的生物活性,是一种潜在的多糖型铁补充剂。                             [16]  Xu L, Meng Y, Liu Y, et al. A novel iron supplements preparation
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