Page 82 - 精细化工2020年第2期

第 37 卷第 2 期 精 细 化 工 Vol.37, No.2
202 0 年 2 月 FINE CHEMICALS Feb. 2020

功能材料
钛酸钡/醋酸纤维素双功能膜的制备及应用

2
1*
郭晓燕 1,2 ，张宝丹 ，靳海波 2,3* ，范代娣
（1. 西北大学 化工学院，陕西 西安 710069；2. 北京石油化工学院 化学工程学院，北京 102617；
3. 燃料清洁化及高效催化减排技术北京市重点实验室，北京 102617）

摘要：以粒径 500 nm 的 BaTiO 3 微球为原料，醋酸纤维素（CA）为粘合剂，制备了具有反射及扩散功能的 BaTiO 3 /CA

双功能膜。利用 SEM、接触角测试仪、紫外-可见分光光度计对 BaTiO 3 /CA 双功能膜进行了表征。考察了 BaTiO 3
形貌、m(CA)∶m(BaTiO 3 )、搅拌时间、表面活性剂种类及用量、固含量、湿膜厚度等对双功能膜形貌、扩散性
能的影响。结果表明，制备 BaTiO 3 /CA 双功能膜的最佳条件为：采用微球 BaTiO 3 ，m(CA)∶m(BaTiO 3 )=0.050∶1，
搅拌时间不少于 4.0 h，表面活性剂为曲拉通 X-100（Triton X-100），添加量为 20 μL/ 10 g BaTiO 3 ，丙酮添加量
为 15 mL，固含量 44.9%，湿膜厚度 0.40 mm。此条件下制备的双功能膜平整、光滑，热稳定性良好。血清经双
功能膜扩散至自制试剂层后，反应形成的斑点颜色均一，5 个平行样品反应斑点直径的标准偏差（SD）为 0.055，
说明扩散均匀且重复性好。此 BaTiO 3 /CA 双功能膜在 460~800 nm 波长内的光反射率大于 97.5%。以此膜制备的
葡萄糖（GLU）、尿酸（URIC）试剂的线性范围较利用 TiO 2 /CA 双功能膜制备的试剂更广，使用更为便捷。
关键词：BaTiO 3 ；醋酸纤维素；双功能膜；干化学（体外）诊断试剂；功能材料
中图分类号：TB383.2 文献标识码：A 文章编号：1003-5214 (2020) 02-0284-06

Preparation and application of bi-functional barium
titanate/cellulose acetate membranes

1*
1,2
2
Guo Xiaoyan , Zhang Baodan , Jin Haibo 2,3* , Fan Daidi
（1. College of Chemical Engineering, Northwest University, Xi′an 710069, Shaanxi, China; 2. College of Chemical
Engineering, Beijing Institute of Petrochemical Technology, Beijing 102617, China; 3. Beijing Key Laboratory of Fuels
Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China）

Abstract: Barium titanate/cellulose acetate (BaTiO 3/CA) membranes with reflection and diffusion
functions were prepared with 500 nm BaTiO 3 microspheres as raw material and cellulose acetate as binder.
SEM, contact angle meter, and UV-visible spectrophotometer were used to characterize the samples. The
effects of BaTiO 3 morphology, mass ratio of CA to BaTiO 3, stirring time, surfactant type and dosage, solid
content and wet film thickness on the morphology and diffusion properties of bi-functional membranes
were studied. The results showed that the optimal conditions for preparing BaTiO 3/CA membranes were as
follows: BaTiO 3 microspheres particle size 500 nm, m(CA)∶m(BaTiO 3)=0.050∶1, stirring time more than
4.0 h, surfactant being Triton X-100, Triton X-100/BaTiO 3 20 μL/10 g, acetone 15 mL, solid content 44.9%,
and wet film thickness 0.40 mm. Under these conditions, the prepared membranes were flat and smooth
with good thermal stablity. After the serum diffused by the bi-functional membrane to the self-made reagent
layer, the spots formed by the reaction were uniform in color. The standard deviation (SD) of the reaction
spot diameter of five parallel samples was 0.055, which showed that the diffusion was uniform and has
good repeatability. The light reflectivity of BaTiO 3/CA membranes in the range of 460~800 nm was over
97.5%. Glucose (GLU) and uric acid (URIC) reagents prepared with BaTiO 3/CA bi-functional membranes
exhibited wider linear ranges than those prepared with TiO 2/CA membranes, which was easier to use.
Key words: BaTiO 3; cellulose acetate; bi-functional membrane; dry chemical diagnostic reagents in vitro;
functional materials

收稿日期：2019-07-24; 定用日期：2019-09-23; DOI: 10.13550/j.jxhg.20190726
基金项目：国家自然科学基金（91634101）；北京市属高校高水平教师队伍建设支持计划高水平创新团队建设计划项目（IDHT20180508）
作者简介：郭晓燕（1982—），女，博士生，讲师。联系人：靳海波（1969—），男，教授，博士，E-mail：jinhaibo@bipt.edu.cn；范
代娣（1966—），女，教授，博士，E-mail：fandaidi@nwu.edu.cn。