Page 117 - 《精细化工》2020年第4期
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第 4 期                  曹亚楠,等:  栀子黄色素富集纯化对其抑制 LDL 氧化修饰的影响                                 ·751·


                (4)GYP-1 能显著抑制 LDL 氧化过程中 CD、                       Lowry,  Bradford Coomassie  blue,  or  the  Smith  Bicinchoninic  acid
                                                                   assay before electrophoresis[J]. Methods in Molecular Biology, 2019,
            MDA 产生,且其抑制效果呈现明显的量效关系。同
                                                                   1855: 31-39.
            浓度 GYP-2 抑制 CD、MDA 产生、LDL 光谱红移                     [15]  YANG Li (杨丽), CHEN Hongping (陈鸿平), LI Xuelian (李雪莲),
                                                                   et al. Correlation between color and pigment components contents of
            等方面显著强于 GYP-1。通过外观颜色及 SEM 观察
                                                                   Lycii fructus  expressing  different  degree  of  color-changing[J].
            表面微观结构,GYP-2 能通过抑制 LDL 氧化而使其                           Chinese Journal of Experimental Traditional Medical Formulae(中国
            颜色及表面微观结构更接近 n-LDL,直观印证了本                              实验方剂学杂志), 2015, 21(8): 47-50.
                                                               [16]  SCHMITZER  V,  MIKULIC-PETKOVSEK  M,  STAMPAR  F, et al.
            文各项生化测定结果,表明 GYP-2 比 GYP-1 对 LDL                       Phenolic accumulation in hybrid primrose and pigment distribution
            氧化修饰的抑制能力更强。                                           in different flower segments[J]. Journal of the American Society for
                                                                   Horticultural Science, 2017, 142(3): 192-199.
                 后续对 GYP-2 继续分离、纯化,其对 LDL 氧                    [17]  ZHOU Wenhong (周文红), LI Jiayi (李家怡), GAO Chenghai (高程
            化修饰的抑制能力可能会进一步增加。本文为后续                                 海), et al. Separation and purification of phenylethanoid glycosides
                                                                   from  the  fruits  of  Avicennia  marina  by  macroporous  adsorption
            抗AS 功能食品及系列GYP 产品研发提供了理论参考。                            resin[J].  Food  Science  and  Technology(食品科技),  2018,  43(1):
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