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·1468·                            精细化工   FINE CHEMICALS                                 第 37 卷

            DPPH•反应体系中,增大唑环共轭结构能够提高                           [13]  PANDEY D  K, KHAKE S M, GONNADE  R G,  et al. Mono- and
                                                                   binuclear  palladacycles  via  regioselective  C–H  bond  activation:
            吡嗪-唑联芳化合物的抗氧化活性。在抑制 AAPH
                                                                   syntheses,  mechanistic  insights  and  catalytic  activity  in  direct
                                            +
            引发的 DNA 氧化反应及淬灭 ABTS •和 DPPH•体系                        arylation of azoles[J]. RSC Advances, 2015, 5(99): 81502-81514.
            中,3 个吡嗪-唑联芳化合物的顺序均为Ⅲc>Ⅲb>                         [14]  KHAKE  S  M,  JAGTAP  R  A,  DANGAT  Y  B,  et al.  Mechanistic
                                                                   insights  into  pincer-ligated  palladium-catalyzed  arylation  of  azoles
            Ⅲa;在抑制 HO•和 GS•引发的 DNA 氧化反应体系                          with  aryl  iodides:  Evidence  of  a  PdⅡ–PdⅣ–PdⅡ pathway[J].
            中,3 个吡嗪-唑联芳化合物抗氧化性能遵循Ⅲb>                              Organometallics, 2016, 35(6): 875-886.
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            Ⅲc>Ⅲa 的规律。                                             amide  bond  formation  reactions  from  carboxylic  acids  and
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            抑制自由基引发 DNA 氧化反应能力,还展现了一定                          [16]  XI G L (席高磊), XU K J (许克静), WANG H W (王宏伟), et al.
            的捕获自由基能力,具有一定的研究前景。这些实                                 Antioxidant  properties  of  4-methyl-7-hydroxycoumarin  and
            验数据为今后继续从事吡嗪-唑联芳类化合物的                                 derivative[J]. Fine Chemicals (精细化工), 2019, 36(6): 1159-1165.
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