Page 163 - 《精细化工》2022年第2期

第 39 卷第 2 期 精 细 化 工 Vol.39, No.2
202 2 年 2 月 FINE CHEMICALS Feb. 2022

医药与日化原料
纳米 SiO /明胶茶油微胶囊的制备及性能
2

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赵国瑜，范方宇 ，槐晋东
（西南林业大学 西南山地森林资源保育与利用教育部重点实验室，生命科学学院，云南省森林灾害预警与
控制重点实验室，云南 昆明 650224）

摘要：为改善茶油微胶囊的稳定性，以活化的纳米 SiO 2 、明胶和酪蛋白酸钠为壁材，玉米糖浆为填充剂，单甘
酯为乳化剂，茶油为芯材，通过喷雾干燥法制备了茶油微胶囊。考察了纳米 SiO 2 添加量（以明胶质量计，下同）
对茶油微胶囊理化性能、热稳定性、表观形态和贮藏稳定性的影响。结果表明，纳米 SiO 2 添加量对制备的茶油
微胶囊的含水率和吸水率没有明显影响。当纳米 SiO 2 添加量为 3%时，茶油微胶囊的综合性能最佳，平均粒径
为(30.55±0.36) μm，包埋率为 92.58%，熔融温度 171.05 ℃，平均粒径比未添加纳米 SiO 2 的茶油微胶囊（空白
样）减少了 7.37%，包埋率和熔融温度分别比空白样增加了 4.80%和 17.83%。该茶油微胶囊表面形态饱满，多
孔结构减弱，具有良好的热稳定性和氧化稳定性。在不同条件下贮藏 35 d 后过氧化值均最低，50 ℃时的过氧
化值为 15.98 mmol/kg，比空白样降低 13.14%。氧化动力学研究结果表明，茶油微胶囊适用于一级反应。
关键词：纳米 SiO 2 ；茶油；微胶囊；贮藏稳定性；氧化动力学；医药原料
中图分类号：TS225.1 文献标识码：A 文章编号：1003-5214 (2022) 02-0367-08

Preparation and properties of nano-SiO 2/gelatin camellia oil microcapsules

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ZHAO Guoyu, FAN Fangyu , HUAI Jindong
（Key Laboratory for Forest Resources Conservation and Utilization, Ministry of Education, College of Life Sciences,
Key Laboratory of Forest Disaster Warning and Control of Yunnan Province, Southwest Forestry University, Kunming
650224, Yunnan, China）

Abstract: In order to improve the stability of camellia oil microcapsules, camellia oil microcapsules were
prepared by spray drying using activated nano-SiO 2, gelatin and sodium caseinate as wall material, corn
syrup as filler, monomeric ester as emulsifier and camellia oil as core material. The effects of nano-SiO 2
additive amount (based on the mass of gelatin, the same below) on the physical and chemical properties,
thermal stability, morphology and storage stability of camellia oil microcapsules were investigated. The
results showed that nano-SiO 2 had no obvious effect on water content and water absorption of camellia oil
microcapsules. When the additive amount of nano-SiO 2 was 3%, the comprehensive properties of camellia
oil microcapsules were the best. The average particle size was (30.55±0.36) μm, which was decreased by
7.37% compared with that of camellia oil microcapsules without addition of nano-SiO 2 (blank sample). The
embedding rate and melting temperature were 92.58% was 171.05 ℃ , respectively, which were
improvement of 4.80 % and 17.83% compared with those of blank sample, respectively. The surface
morphology of camellia oil microcapsules was full and dense without any cracks and the porous structure
was weakened. The camellia oil microcapsules had good thermal and oxidative stability. Peroxide value of
the camellia oil microcapsules were the lowest after 35 d storage under different conditions. The peroxide
value was 15.98 mmol/kg at 50 ℃, which decreased by 13.14% compared with that of blank sample. The
results of oxidation kinetics indicated that the oxidation progress of camellia oil microcapsules was suitable
for the first-order reaction.
Key words: nano-SiO 2; camellia oil; microcapsule; storage stability; oxidation kinetics; drug materials

收稿日期：2021-08-14; 定用日期：2021-09-30; DOI: 10.13550/j.jxhg.20210820
基金项目：国家自然科学基金（31760470）；云南省“万人计划”青年拔尖人才专项资助（YNWR-QNBJ-2018-046）
作者简介：赵国瑜（1997—），女，硕士生，E-mail：zhaoguoyu320@163.com。联系人：范方宇（1979—），男，教授，E-mail：ffy118@163.com。