Page 122 - 201903
P. 122
·468· 精细化工 FINE CHEMICALS 第 36 卷
polysaccharides from Cordyceps cicadas[J]. Food Science (食品科
学), 2016, 37(13): 19-24.
3 结论 [13] Li Nan (李楠), Shi Junling (师俊玲), Wang Kun (王昆). Composition
and in vitro antioxidant activity of polyphenols extracted from
模拟体外消化可显著增加蓝莓提取物总酚含 crabapple[J]. Food Science (食品科学), 2014, 35(5): 53-58.
[14] Guo Xiaoxuan (郭孝萱), Liu Jia (柳嘉), Lu Xuejiao (陆雪娇), et al.
量,降低总花色苷含量。对比消化前后样品的抗氧 Comparing of ethanol extracts from three fungi fermented
purple-fleshed potatoes on total phenolic content, flavonoids,
化活性发现,胃肠消化能显著提高脂质体抑制率、 anthocyanins, antioxidant activities and cytotoxicity on HepG2
+
DPPH 自由基清除率和 ABTS 自由基清除率,且清 cells[J]. Journal of Chinese Institute of Food Science and Technology
(中国食品学报), 2017, 17(3): 289-295.
除率均显著高于对照组 V C 。对比消化前后不同质量 [15] Toydemir G, Capanoglu E, Kamiloglu S, et al. Changes in sour
cherry (Prunus cerasus, L.) antioxidants during nectar processing
浓度的样品对 HepG2 肝癌细胞、A549 肺癌细胞和 and in vitro, gastrointestinal digestion[J]. Journal of Functional
Foods, 2013, 5(3): 1402-1413.
Hela 人宫颈癌细胞存活率发现,随质量浓度的增加, [16] Lee J, Durst R W, Wrolstad R E. Determination of total monomeric
3 种癌细胞的存活率显著降低,经体外消化后 3 种 anthocyanin pigment content of fruit juices, beverages, natural
colorants, and wines by the pH differential method: Collaborative
癌细胞存活率明显低于未消化样品。结果表明,体 study[J]. Journal of Aoac International, 2005, 88(5): 1269-1278.
[17] Bao J, Cai Y, Sun M, et al. Anthocyanins, flavonols, and free radical
外消化后样品对 3 种癌细胞的生长抑制作用显著增 scavenging activity of Chinese bayberry (Myrica rubra) extracts and
加,此抗癌功效可能与消化后降解产生的酚类物质 their color properties and stability[J]. Journal of Agricultural & Food
Chemistry, 2005, 53(6): 2327-2332.
有关。通过 HPLC-ESI-MS 分析发现,蓝莓提取物包 [18] Sun D, Huang S, Cai S, et al. Digestion property and synergistic
effect on biological activity of purple rice (Oryza sativa L.)
含 12 种花色苷组分。经胃消化后,飞燕草-3-葡萄 anthocyanins subjected to a simulated gastrointestinal digestion in
vitro[J]. Food Research International, 2015, 78: 114-123.
糖苷和矢车菊-3-葡萄糖苷消失;经肠消化后,飞燕 [19] Yang Z D, Zhai W W. Identification and antioxidant activity of
草-3-葡萄糖苷、矢车菊-3-葡萄糖苷和天竺葵-3-半乳 anthocyanins extracted from the seed and cob of purple corn (Zea
mays L.)[J]. Innovative Food Science & Emerging Technologies,
糖苷均消失。对胃肠消化花色苷的降解过程推测, 2010, 11(1):169-176.
[20] Huang H, Sun Y, Lou S, et al. In vitro digestion combined with
发现矢车菊素-3-葡萄糖苷降解形成槲皮素与天竺 cellular assay to determine the antioxidant activity in Chinese
葵素- 3-葡萄糖苷降解成山柰酚过程的机制相同。花 bayberry (Myrica rubra Sieb. et Zucc.) fruits: A comparison with
traditional methods[J]. Food Chemistry, 2014, 146(146): 363-370.
色苷更为详尽的降解过程仍需进一步研究。 [21] Tagliazucchi D, Verzelloni E, Bertolini D, et al. In vitro
bio-accessibility and antioxidant activity of grape polyphenols[J].
Food Chemistry, 2010, 120(2): 599-606.
参考文献: [22] Prasad N R, Karthikeyan S, Reddy B V. Inhibitory effect of caffeic
[1] Zhao Zidan (赵子丹), Ge Qian (葛谦), Niu Yan (牛艳), et al. acid on cancer cell proliferation by oxidative mechanism in human
Determination of anthocyanidins in Lycium ruthenicum Murr. by HT-1080 fibrosarcoma cell line[J]. Molecular & Cellular
HPLC[J]. Food Research and Development (食品研究与开发), Biochemistry, 2011, 349(1/2): 11-19.
2017, 38(12): 123-129. [23] Munoz-Espada A C, Watkins B A. Cyanidin attenuates PGE 2
[2] Pertuzatti P B, Barcia M T, Rebello L P G, et al. Antimicrobial production and cyclooxygenase-2 expression in LNCaP human
activity and differentiation of anthocyanin profiles of rabbit eye and prostate cancer cells[J]. Journal of Nutritional Biochemistry, 2006,
high bush blueberries using HPLC-DAD-ESI-MS n, and multivariate 17(9): 589-596.
analysis[J]. Journal of Functional Foods, 2016, 26: 506-516. [24] Lee Y S. Role of NADPH oxidase-mediated generation of reactive
[3] Sarkis J R, Jaeschke D P, Tessaro I C, et al. Effects of ohmic and oxygen species in the mechanism of apoptosis induced by phenolic
conventional heating on anthocyanin degradation during the acids in HepG2 human hepatoma cells[J]. Archives of Pharmacal
processing of blueberry pulp[J]. LWT-Food Science and Technology, Research, 2005, 28(10): 1183-1189.
2013, 51(1): 79-85. [25] Chen P N, Chu S C, Chiou H L, et al. Mulberry anthocyanins,
[4] Manach C, Williamson Gmorand C, Scalbert A, et al. Bioavailability cyanidin-3-rutinoside and cyanidin 3-glucoside, exhibited an
and bioefficacy of polyphenols in humans. I. Review of 97 inhibitory effect on the migration and invasion of a human lung
bioavailability studies[J]. American Journal of Clinical Nutrition, cancer cell line[J]. Cancer Letters, 2006, 235(2): 248-259.
2005, 81: S230- S242. [26] Chen Jianyang ( 陈建杨 ). Study on anti-cancer activity of
[5] Wang Yuehua (王月华), Li Bin (李斌), Meng Xianjun (孟宪军), et anthocyanin-rich extracts from speciality potatoes in vitro[D].
al. Effect of in vitro simulated digestion on anthocyanin composition Hangzhou:Zhejiang University (杭州:浙江大学), 2013.
and antioxidant activity of Lonicera caerulea berry Extracts[J]. Food [27] Seeram N P, Adams L S, Zhang Y, et al. Blackberry, black
Science (食品科学), 2016, 37(19): 100-105. raspberry, blueberry, cranberry, red raspberry, and strawberry
[6] Vitaglione P, Donnarumma G, Napolitano A, et al. Protocatechuic extracts inhibit growth and stimulate apoptosis of human cancer cells
acid is the major human metabolite of cyanidin-glucosides[J]. The in vitro[J]. Journal of Agricultural & Food Chemistry, 2006, 54(25):
Journal of Nutrition, 2007, 137(9), 2043-2048. 9329-9339.
[7] Lv Chunmao (吕春茂), Bao Jing (包静), Meng Xianjun (孟宪军), et [28] Nicoué E E, Savard S, Belkacemi K. Anthocyanins in wild
al. Separation of anthocyanins from wild bilberry by HPD-700 blueberries of Quebec: extraction and identification[J]. Journal of
macroporous resin[J]. Food Science (食品科学), 2012, 33(10): 78-83. Agricultural & Food Chemistry, 2007, 55(14): 5626-5635.
[8] Ryu D, Koh E. Stability of anthocyanins in bokbunja (Rubus [29] Sun L Q, Ding X P, Qi J, et al. Antioxidant anthocyanins screening
occidentalis L.) under in vitro gastrointestinal digestion[J]. Food through spectrum-effect relationships and DPPH-HPLC-DAD
Chemistry, 2018, 267, 157-162. analysis on nine cultivars of introduced rabbiteye blueberry in
[9] Koyu H, Kazan A, Demir S, et al. Optimization of microwave China[J]. Food Chemistry, 2012, 132(2): 759-765.
assisted extraction of Morus nigra L. fruits maximizing tyrosinase [30] Liu Y, Song X, Han Y, et al. Identification of anthocyanin components
inhibitory activity with isolation of bioactive constituents[J]. Food of wild Chinese blueberries and amelioration of light-induced retinal
Chemistry, 2018, 248: 183-191. damage in pigmented rabbit using whole berries[J]. Journal of
[10] Yu Zeyuan (于泽源), Zhao Jianhui (赵剑辉), Li Xingguo (李兴国), Agricultural & Food Chemistry, 2011, 59(1): 356-363.
et al. Isolation and purification of anthocyanin from blueberry by [31] Gong Hui (龚辉), Fu Li (傅丽), Li Lanqi (李澜奇), et al. Effect of
sequential medium pressure column chromatography on ultrasound treatment on anthocyanin stability and degradation
macroporous resin and Sephadex LH-20[J]. Food Science (食品科 kinetics[J]. Food Science (食品科学), 2018, 39(9): 67-75.
学), 2018, 39(1): 118-123. [32] Furtado P, Figueiredo P, Neves H C D, et al. Photochemical and
[11] Li Yingchang (李颖畅), Li Bingxin (李冰心), Meng Liangyu (孟良 thermal degradation of anthocyanidins[J]. Journal of Photochemistry
玉), et al. Antioxidant activity and stability of anthocyanins from St. & Photobiology A Chemistry, 1993, 75(2): 113-118.
Cloud blueberry[J]. Food Science (食品科学), 2012, 33(9): 105-109. [33] Lopes P, Richard T, Saucier C, et al. Anthocyanone A: A quinone
[12] Feng Yan (封燕), Gong Xiaohui (贡小辉), Wei Dequn (韦德群), et methide derivative resulting from malvidin-3-O-glucoside degradation[J].
al. Antioxidant activity and preliminary structure analysis of Journal of Agricultural and Food Chemistry, 2007, 55(7): 2698-2704.