Page 171 - 《精细化工》2023年第12期

第 12 期 邵越楣，等: 不同超声辅助提取桂花黄酮及其抑菌性 ·2713·

的重要方面，与致病性和在宿主内稳定性存在密切 Profuse diversity and acidogenicity of the candida-biome of deep
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酮对生物膜早期形成的抑制作用。如图 4 所示，与 [3] NDEKERO T S, CARNEIRO L C, MASUMO R M. Prevalence of
对照组相比，不同品种的桂花黄酮对 C. albicans 的 early childhood caries, risk factors and nutritional status among
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生物膜形成都有显著的抑制作用，但 4 个品种之间 2021, 16(2): e0247240.
没有显著性差异。当处理 4 h 后，丹桂黄酮对 C. [4] KAZEMINIA M, ABDI A, SHOHAIMI S, et al. Dental caries in
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弱；处理 24 h 后，四季桂黄酮对生物膜的抑制率最
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Extraction optimization by response surface methodology of active
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MS/MS 结果表明，桂花黄酮中含有白麻苷、6-羟基 Fine Chemicals (精细化工), 2023, 40(1): 101-108.
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Chemistry Letters, 2015, 25(10): 2068-2073.
素-3-O-洋槐糖苷等 211 种化合物。以 C. albicans 为 [15] CHENG X M, YANG Y, ZHU X G, et al. Inhibitory mechanisms of
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抑菌效果，其中金桂的抑菌效果最好，MIC 值为 1.50 [16] WANG Y, LIU X Y, CHEN T, et al. Antifungal effects of hinokitiol
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酮处理 C. albicans 24 h 内，菌体细胞的细胞膜结构
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后期生物膜逐渐成熟，抑制作用逐渐减弱。本研究
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为天然化合物抑制 C. albicans 的效果提供了参考， Dictyophora[D]. Fuzhou: Fujian Agriculture and Forestry University
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的抑制效果，探究发挥抑菌效果的主要化合物，并 mold and sour rot in citrus fruits by the cationic antimicrobial peptide
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[1] FAKHRUDDIN K S, SAMARANAYAKE L P, EGUSA H, et al. （下转第 2730 页）